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  • The mobile element that conveys methicillin resistance to staph includes a gene that encodes for Cch. Learn more about Phoebe Rice's Chicago lab.

  • AlkD (grey) crystal structure bound to DNA containing 3-deaza-3-methyldeoxyadenosine (light green), from Brandt Eichman. Read the full story.

  • Jalview Developer Geoff Barton's desk with the JalviewAbacus (right) and displayed a dendrogram (tree) for the set of sequences shown in the alignment, using Jalview linked to Chimera. Read the full story here.

  • Project MAC display system, circa 1965,

    The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • You'll find SBGrid in ~350 structural biology labs located at over 100 different institutions in about 20 countries around the world. See full map and read more in eLIFE.

  • Daniel Panne's group, which relocated in 2018 to the University of Leicester, looks at the language of gene regulation and visualizes the catalytic core of p300. Read the full story.

  • Professor Catherine Drennan of MIT

    The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE.

  • The AdipoR2 structure revealing the presence of a bound fatty acid at a zinc binding site, from Sebastien Granier's lab at the French National Institute of Health and Medical Research (INSERM), Institut de Génomique Fonctionnelle, Montpellier France. Read more.

  • Tom Rapoport's group at Harvard Medical School captured the crystal structure of the active translocon being pushed through the hourglass-shaped SecY protein-conducting channel. You can find out more about the science and learn some personal history in our Member Tale.

  • The first high-resolution (2.8 Å) X-ray crystal structure of the transcription initiation complex of Mycobacterium smegmatis, from the laboratory of Seth Darst at Rockefeller University.

    Image courtesy of E. Campbell.

  • In traditional X-ray crystallography, X-rays bombard 1 crystal 100s of times. This syringe, developed for a dynamic temperature experiment in James Fraser's lab at UCSF, shoots 1,000s of crystals into an X-ray-free electron laser beam, one at a time. Learn more.

    Image courtesy of Alexander Wolff.

Recent Software Updates

May 26 | pyemma

a Python library for the estimation, validation and analysis Markov models of molecular kinetics and other kinetic and thermodynamic models… >>
May 26 | CTFFIND 4

a new version of ctffind (a program for finding CTFs of electron micrographs) that should run significantly faster than CTFFIND 3 and may g… >>
May 26 | DataWarrior

an Open-Source Program for Data Visualization and Analysis with Chemical Intelligence >>
May 25 | GROMACS

a versatile package that performs molecular dynamics of proteins, lipids and nucleic acids. >>
May 24 | ChimeraX

the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UC… >>
May 23 | RELION

(REgularised LIkelihood OptimisatioN) a stand-alone computer program for Maximum A Posteriori (MAP) refinement of (multiple) 3D reconstruct… >>
May 23 | CUDA

redistributable software libraries to support CUDA applications for Linux. >>
Thanks to the National Science Foundation

With Partial Support from the National Science Foundation Research Coordination Network MCB #0639193 and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

SBGrid/Harvard Shield

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - hear from software developers about what's new in structural biology. Community members can connect via Zoom and …

NE-CAT Practical Crystallography Course

NE-CAT is pleased to offer our Practical Crystallography Course, June 21-23, 2023 at Harvard Medical School in Boston, Massachusetts. The course will be a three day workshop hosted in conjunction …

Second Takes

Second Takes

Andrea Thorn had been a junior group leader for a less than a year when, in early January 2020, researchers in China identified the cause of a mysterious contagious illness …

Floppy Physics

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At the heart of human cells, tiny protein tubes radiate out in all directions. Anchored near the nucleus, they help cells hold their shape, organize internal components, and in dividing …

Member publications

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