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33 Member Publications for June

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Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.
1. Elife - published June 8, 2018
2. Miles TF, Spiess K, Jude KM, Tsutsumi N, Burg JS, Ingram JR, Waghray D, Hjorto GM, Larsen O, Ploegh HL, Rosenkilde MM, Garcia KC
Assembly of human C-terminal binding protein (CtBP) into tetramers.
1. J Biol Chem - published June 8, 2018
2. Bellesis AG, Jecrois AM, Hayes JA, Schiffer CA, Royer WE Jr
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
1. Elife - published June 7, 2018
2. Keedy DA, Hill ZB, Biel JT, Kang E, Rettenmaier TJ, Brandao-Neto J, Pearce NM, von Delft F, Wells JA, Fraser JS
Role of Liquid-Liquid Phase Separation in Assembly of Elastin and Other Extracellular Matrix Proteins.
1. J Mol Biol - published June 7, 2018
2. Muiznieks LD, Sharpe S, Pomès R, Keeley FW
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
1. Mol Cell - published June 7, 2018
2. Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW Jr, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE
Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice.
1. Psychopharmacology (Berl) - published June 7, 2018
2. Shi J, Liu H, Pan J, Chen J, Zhang N, Liu K, Fei N, O'Donnell JM, Zhang HT, Xu Y
Vms1p is a release factor for the ribosome-associated quality control complex.
1. Nat Commun - published June 6, 2018
2. Zurita Rendón O, Fredrickson EK, Howard CJ, Van Vranken J, Fogarty S, Tolley ND, Kalia R, Osuna BA, Shen PS, Hill CP, Frost A, Rutter J
FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete Leptospira.
1. Front Cell Infect Microbiol - published June 6, 2018
2. Wunder EA Jr, Slamti L, Suwondo DN, Gibson KH, Shang Z, Sindelar CV, Trajtenberg F, Buschiazzo A, Ko AI, Picardeau M
Determinants of human Glucokinase activation and implications for small molecule allosteric control.
1. Biochim Biophys Acta - published June 6, 2018
2. Li Q, Gakhar L, Ashley Spies M
Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28.
1. Cell Rep - published June 5, 2018
2. Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W, Heffron GJ, Daley GQ, Sliz P
Type 1 Does The Two-Step: Type 1 Secretion Substrates With A Functional Periplasmic Intermediate.
1. J Bacteriol - published June 4, 2018
2. Smith TJ, Sondermann H, O'Toole GA
Cyclin A Turns on Bora to Light the Path to Mitosis.
1. Dev Cell - published June 4, 2018
2. Zheng G, Yu H
Structure-based discovery of selective BRPF1 bromodomain inhibitors.
1. Eur J Med Chem - published June 2, 2018
2. Zhu J, Zhou C, Caflisch A
The Yin and Yang of SagS: Distinct Residues in the HmsP Domain of SagS Independently Regulate Biofilm Formation and Biofilm Drug Tolerance.
1. mSphere - published June 2, 2018
2. Dingemans J, Poudyal B, Sondermann H, Sauer K
Structural basis of mitochondrial receptor binding and constriction by DRP1.
1. Nature - published June 1, 2018
2. Kalia R, Wang RY, Yusuf A, Thomas PV, Agard DA, Shaw JM, Frost A
New Insights into Ribosome Structure and Function.
1. Cold Spring Harb Perspect Biol - published June 1, 2018
2. Jobe A, Liu Z, Gutierrez-Vargas C, Frank J
A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high-order assembly of a vimentin filament.
1. FEBS J - published June 1, 2018
2. Pang AH, Obiero JM, Kulczyk AW, Sviripa VM, Tsodikov OV
A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System.
1. Cell - published June 1, 2018
2. Qin Y, Garrison BS, Ma W, Wang R, Jiang A, Li J, Mistry M, Bronson RT, Santoro D, Franco C, Robinton DA, Stevens B, Rossi DJ, Lu C, Springer TA
Heterocycles: Versatile control elements in bioactive macrocycles.
1. Bioorg Med Chem - published June 1, 2018
2. Soor HS, Appavoo SD, Yudin AK
RGG/RG Motif Regions in RNA Binding and Phase Separation.
1. J Mol Biol - published June 1, 2018
2. Chong PA, Vernon RM, Forman-Kay JD
Does Hormone Therapy Use Increase Perioperative Complications in Abdominally Based Microsurgical Breast Reconstruction?
1. Plast Reconstr Surg - published June 1, 2018
2. Tran BNN, Ruan QZ, Cohen JB, Kamali P, Doval AF, Tobias AM, Singhal D, Lin SJ, Lee BT
Flagellum inheritance in Trypanosoma brucei requires a kinetoplastid-specific protein phosphatase.
1. J Biol Chem - published June 1, 2018
2. Zhou Q, Dong G, Li Z
cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud.
1. J Struct Biol - published June 1, 2018
2. Cianfrocco MA, Lahiri I, DiMaio F, Leschziner AE
The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.
1. J Biol Chem - published June 1, 2018
2. Weinhäupl K, Brennich M, Kazmaier U, Lelievre J, Ballell L, Goldberg A, Schanda P, Fraga H
Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state.
1. Nat Struct Mol Biol - published June 1, 2018
2. Lei HT, Ma J, Sanchez Martinez S, Gonen T
X-ray structural, functional and computational studies of the O2-sensitive E. coli hydrogenase-1 C19G variant reveal an unusual [4Fe-4S] cluster.
1. Chem Commun (Camb) - published June 1, 2018
2. Volbeda A, Mouesca JM, Darnault C, Roessler MM, Parkin A, Armstrong FA, Fontecilla-Camps JC
Plasticity in binding confers selectivity in ligand-induced protein degradation.
1. Nat Chem Biol - published June 1, 2018
2. Nowak RP, DeAngelo SL, Buckley D, He Z, Donovan KA, An J, Safaee N, Jedrychowski MP, Ponthier CM, Ishoey M, Zhang T, Mancias JD, Gray NS, Bradner JE, Fischer ES
The crystal structure of the Helicobacter pylori LlaJI.R1 N-terminal domain provides a model for site-specific DNA binding.
1. J Biol Chem - published June 1, 2018
2. Hosford CJ, Chappie JS
Structure of the µ-opioid receptor-Gi protein complex.
1. Nature - published June 1, 2018
2. Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
1. Nature - published June 1, 2018
2. Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE
Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
1. Nat Commun - published June 1, 2018
2. Lin DH, Correia AR, Cai SW, Huber FM, Jette CA, Hoelz A
Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.
1. Proc Natl Acad Sci U S A - published June 1, 2018
2. Bleichert F, Leitner A, Aebersold R, Botchan MR, Berger JM
Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
1. Nature - published June 1, 2018
2. Chen MC, Tippana R, Demeshkina NA, Murat P, Balasubramanian S, Myong S, Ferré-D'Amaré AR

Member Publications

33 Member Publications for June

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

Assembly of human C-terminal binding protein (CtBP) into tetramers.

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.

Role of Liquid-Liquid Phase Separation in Assembly of Elastin and Other Extracellular Matrix Proteins.

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

Inhibition of phosphodiesterase 2 by Bay 60-7550 decreases ethanol intake and preference in mice.

Vms1p is a release factor for the ribosome-associated quality control complex.

FcpB Is a Surface Filament Protein of the Endoflagellum Required for the Motility of the Spirochete <i>Leptospira</i>.

Determinants of human Glucokinase activation and implications for small molecule allosteric control.

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28.

Type 1 Does The Two-Step: Type 1 Secretion Substrates With A Functional Periplasmic Intermediate.

Cyclin A Turns on Bora to Light the Path to Mitosis.

Structure-based discovery of selective BRPF1 bromodomain inhibitors.

The Yin and Yang of SagS: Distinct Residues in the HmsP Domain of SagS Independently Regulate Biofilm Formation and Biofilm Drug Tolerance.

Structural basis of mitochondrial receptor binding and constriction by DRP1.

New Insights into Ribosome Structure and Function.

A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high-order assembly of a vimentin filament.

A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System.

Heterocycles: Versatile control elements in bioactive macrocycles.

RGG/RG Motif Regions in RNA Binding and Phase Separation.

Does Hormone Therapy Use Increase Perioperative Complications in Abdominally Based Microsurgical Breast Reconstruction?

Flagellum inheritance in <i>Trypanosoma brucei</i> requires a kinetoplastid-specific protein phosphatase.

cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud.

The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from <i>Mycobacterium tuberculosis</i>.

Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state.

X-ray structural, functional and computational studies of the O<sub>2</sub>-sensitive E. coli hydrogenase-1 C19G variant reveal an unusual [4Fe-4S] cluster.

Plasticity in binding confers selectivity in ligand-induced protein degradation.

The crystal structure of the <i>Helicobacter pylori</i> LlaJI.R1 N-terminal domain provides a model for site-specific DNA binding.

Structure of the µ-opioid receptor-G<sub>i</sub> protein complex.

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.

Structural and functional analysis of mRNA export regulation by the nuclear pore complex.

Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.

Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.