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41 Member Publications for March

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Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage.
1. Methods Enzymol - published March 10, 2019
2. Morgan M, Jbara M, Brik A, Wolberger C
How has DSM-5 Affected Autism Diagnosis? A 5-Year Follow-Up Systematic Literature Review and Meta-analysis.
1. J Autism Dev Disord - published March 9, 2019
2. Kulage KM, Goldberg J, Usseglio J, Romero D, Bain JM, Smaldone AM
An alternative N-terminal fold of the intestine-specific annexin A13a induces dimerization and regulates membrane-binding.
1. J Biol Chem - published March 8, 2019
2. McCulloch KM, Yamakawa I, Shifrin DA Jr, McConnell RE, Foegeding NJ, Singh PK, Mao S, Tyska MJ, Iverson TM
Successful Aspects of the Coadministration of Sterol 14α-Demethylase Inhibitor VFV and Benznidazole in Experimental Mouse Models of Chagas Disease Caused by the Drug-Resistant Strain of Trypanosoma cruzi.
1. ACS Infect Dis - published March 8, 2019
2. Guedes-da-Silva FH, Batista DDGJ, Da Silva CF, Pavão BP, Batista MM, Moreira OC, Souza LRQ, Britto C, Rachakonda G, Villalta F, Lepesheva GI, Soeiro MNC
The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy.
1. Nat Commun - published March 8, 2019
2. Wang GZ, Zhang L, Zhao XC, Gao SH, Qu LW, Yu H, Fang WF, Zhou YC, Liang F, Zhang C, Huang YC, Liu Z, Fu YX, Zhou GB
Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor.
1. Science - published March 8, 2019
2. Bräuer P, Parker JL, Gerondopoulos A, Zimmermann I, Seeger MA, Barr FA, Newstead S
A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.
1. Science - published March 8, 2019
2. Huang WYC, Alvarez S, Kondo Y, Lee YK, Chung JK, Lam HYM, Biswas KH, Kuriyan J, Groves JT
A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state.
1. Nat Commun - published March 7, 2019
2. Rizzolo K, Cohen SE, Weitz AC, López Muñoz MM, Hendrich MP, Drennan CL, Elliott SJ
Evidence for hormonal control of heart regenerative capacity during endothermy acquisition.
1. Science - published March 7, 2019
2. Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, Field KA, Reeder DM, Maden M, Yartsev MM, Wolfgang MJ, Grützner F, Scanlan TS, Szweda LI, Buffenstein R, Hu G, Flamant F, Olgin JE, Huang GN
Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids.
1. Nat Commun - published March 7, 2019
2. Liberta F, Loerch S, Rennegarbe M, Schierhorn A, Westermark P, Westermark GT, Hazenberg BPC, Grigorieff N, Fändrich M, Schmidt M
Discovery and structure of the antimicrobial lasso peptide citrocin.
1. J Biol Chem - published March 7, 2019
2. Cheung-Lee WL, Parry ME, Jaramillo Cartagena A, Darst SA, Link AJ
Maturation of the respiratory complex II flavoprotein.
1. Curr Opin Struct Biol - published March 6, 2019
2. Sharma P, Maklashina E, Cecchini G, Iverson TM
Cheating Death: New Molecules Block BAX.
1. Trends Mol Med - published March 6, 2019
2. Walensky LD
Human DNA polymerase η has reverse transcriptase activity in cellular environments.
1. J Biol Chem - published March 6, 2019
2. Su Y, Ghodke PP, Egli M, Li L, Wang Y, Guengerich FP
Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies.
1. Sci Rep - published March 5, 2019
2. Bajic G, van der Poel CE, Kuraoka M, Schmidt AG, Carroll MC, Kelsoe G, Harrison SC
Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes.
1. ACS Infect Dis - published March 5, 2019
2. Markley JL, Fang L, Gasparrini AJ, Symister CT, Kumar H, Tolia NH, Dantas G, Wencewicz TA
Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX.
1. Structure - published March 5, 2019
2. De I, Chittock EC, Grötsch H, Miller TCR, McCarthy AA, Müller CW
Structural Principles in Robo Activation and Auto-inhibition.
1. Cell - published March 4, 2019
2. Barak R, Yom-Tov G, Guez-Haddad J, Gasri-Plotnitsky L, Maimon R, Cohen-Berkman M, McCarthy AA, Perlson E, Henis-Korenblit S, Isupov MN, Opatowsky Y
Past and future spread of the arbovirus vectors Aedes aegypti and Aedes albopictus.
1. Nat Microbiol - published March 4, 2019
2. Kraemer MUG, Reiner RC Jr, Brady OJ, Messina JP, Gilbert M, Pigott DM, Yi D, Johnson K, Earl L, Marczak LB, Shirude S, Davis Weaver N, Bisanzio D, Perkins TA, Lai S, Lu X, Jones P, Coelho GE, Carvalho RG, Van Bortel W, Marsboom C, Hendrickx G, Schaffner F, Moore CG, Nax HH, Bengtsson L, Wetter E, Tatem AJ, Brownstein JS, Smith DL, Lambrechts L, Cauchemez S, Linard C, Faria NR, Pybus OG, Scott TW, Liu Q, Yu H, Wint GRW, Hay SI, Golding N
Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.
1. FEBS Lett - published March 1, 2019
2. How JY, Caria S, Humbert PO, Kvansakul M
Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain.
1. ACS Chem Biol - published March 1, 2019
2. McNally R, Li Q, Li K, Dekker C, Vangrevelinghe E, Jones M, Chène P, Machauer R, Radimerski T, Eck MJ
Resistance outside the substrate envelope: hepatitis C NS3/4A protease inhibitors.
1. Crit Rev Biochem Mol Biol - published March 1, 2019
2. Özen A, Prachanronarong K, Matthew AN, Soumana DI, Schiffer CA
MXCuBE2: the dawn of MXCuBE Collaboration.
1. J Synchrotron Radiat - published March 1, 2019
2. Oscarsson M, Beteva A, Flot D, Gordon E, Guijarro M, Leonard G, McSweeney S, Monaco S, Mueller-Dieckmann C, Nanao M, Nurizzo D, Popov AN, von Stetten D, Svensson O, Rey-Bakaikoa V, Chado I, Chavas LMG, Gadea L, Gourhant P, Isabet T, Legrand P, Savko M, Sirigu S, Shepard W, Thompson A, Mueller U, Nan J, Eguiraun M, Bolmsten F, Nardella A, Milàn-Otero A, Thunnissen M, Hellmig M, Kastner A, Schmuckermaier L, Gerlach M, Feiler C, Weiss MS, Bowler MW, Gobbo A, Papp G, Sinoir J, McCarthy AA, Karpics I, Nikolova M, Bourenkov G, Schneider T, Andreu J, Cuní G, Juanhuix J, Boer R, Fogh R, Keller P, Flensburg C, Paciorek W, Vonrhein C, Bricogne G, de Sanctis D
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O2 activation.
1. Proc Natl Acad Sci U S A - published March 1, 2019
2. Appel MJ, Meier KK, Lafrance-Vanasse J, Lim H, Tsai CL, Hedman B, Hodgson KO, Tainer JA, Solomon EI, Bertozzi CR
Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
1. Nat Commun - published March 1, 2019
2. Furlong EJ, Lo AW, Kurth F, Premkumar L, Totsika M, Achard MES, Halili MA, Heras B, Whitten AE, Choudhury HG, Schembri MA, Martin JL
Structural basis for KCTD-mediated rapid desensitization of GABAB signalling.
1. Nature - published March 1, 2019
2. Zheng S, Abreu N, Levitz J, Kruse AC
Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses.
1. Nat Immunol - published March 1, 2019
2. Kanekiyo M, Joyce MG, Gillespie RA, Gallagher JR, Andrews SF, Yassine HM, Wheatley AK, Fisher BE, Ambrozak DR, Creanga A, Leung K, Yang ES, Boyoglu-Barnum S, Georgiev IS, Tsybovsky Y, Prabhakaran MS, Andersen H, Kong WP, Baxa U, Zephir KL, Ledgerwood JE, Koup RA, Kwong PD, Harris AK, McDermott AB, Mascola JR, Graham BS
IL (Interleukin)-33 Suppresses Abdominal Aortic Aneurysm by Enhancing Regulatory T-Cell Expansion and Activity.
1. Arterioscler Thromb Vasc Biol - published March 1, 2019
2. Li J, Xia N, Wen S, Li D, Lu Y, Gu M, Tang T, Jiao J, Lv B, Nie S, Liao M, Liao Y, Yang X, Hu Y, Shi GP, Cheng X
The Dynamic Structures of the Type IV Pilus.
1. Microbiol Spectr - published March 1, 2019
2. McCallum M, Burrows LL, Howell PL
Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity.
1. Genes Dev - published March 1, 2019
2. Shimojo M, Madara J, Pankow S, Liu X, Yates J 3rd, Südhof TC, Maximov A
Fine tuning of σE activation suppresses multiple assembly-defective mutations in Escherichia coli.
1. J Bacteriol - published March 1, 2019
2. Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, Silhavy TJ
How Second Coordination Sphere Modifications Can Impact Metal Structures in Proteins: A Crystallographic Evaluation.
1. Chemistry - published March 1, 2019
2. Pecoraro VL, Ruckthong L, Stuckey JA
Global Outbreaks and Origins of a Chikungunya Virus Variant Carrying Mutations Which May Increase Fitness for Aedes aegypti: Revelations from the 2016 Mandera, Kenya Outbreak.
1. Am J Trop Med Hyg - published March 1, 2019
2. Maljkovic Berry I, Eyase F, Pollett S, Konongoi SL, Joyce MG, Figueroa K, Ofula V, Koka H, Koskei E, Nyunja A, Mancuso JD, Jarman RG, Sang R
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
1. Cell Rep - published March 1, 2019
2. Aho ER, Wang J, Gogliotti RD, Howard GC, Phan J, Acharya P, Macdonald JD, Cheng K, Lorey SL, Lu B, Wenzel S, Foshage AM, Alvarado J, Wang F, Shaw JG, Zhao B, Weissmiller AM, Thomas LR, Vakoc CR, Hall MD, Hiebert SW, Liu Q, Stauffer SR, Fesik SW, Tansey WP
A multi-targeted probe-based strategy to identify signaling vulnerabilities in cancers.
1. J Biol Chem - published March 1, 2019
2. Rao S, Du G, Hafner M, Subramanian K, Sorger PK, Gray NS
Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination.
1. Chem Commun (Camb) - published March 1, 2019
2. Saez Cabodevilla J, Volbeda A, Hamelin O, Latour JM, Gigarel O, Clémancey M, Darnault C, Reichmann D, Amara P, Fontecilla-Camps JC, Ollagnier de Choudens S
Aromatic 19F-13C TROSY: a background-free approach to probe biomolecular structure, function, and dynamics.
1. Nat Methods - published March 1, 2019
2. Boeszoermenyi A, Chhabra S, Dubey A, Radeva DL, Burdzhiev NT, Chanev CD, Petrov OI, Gelev VM, Zhang M, Anklin C, Kovacs H, Wagner G, Kuprov I, Takeuchi K, Arthanari H
The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency.
1. Sci Rep - published March 1, 2019
2. Manczyk N, Veggiani G, Teyra J, Strilchuk AW, Sidhu SS, Sicheri F
Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ.
1. IUCrJ - published March 1, 2019
2. Zee CT, Glynn C, Gallagher-Jones M, Miao J, Santiago CG, Cascio D, Gonen T, Sawaya MR, Rodriguez JA
CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement.
1. Nat Commun - published March 1, 2019
2. Vassal-Stermann E, Effantin G, Zubieta C, Burmeister W, Iseni F, Wang H, Lieber A, Schoehn G, Fender P
Structural mechanisms of phospholipid activation of the human TPC2 channel.
1. Elife - published March 1, 2019
2. She J, Zeng W, Guo J, Chen Q, Bai X, Jiang Y