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  • The SBGrid Consortium provides structural biologists worldwide with access to the software they need to discover the shapes of the molecules of life. Read more in eLIFE and Acta Cryst.

  • SBCloud: AWS platform optimized for structural biology; pre-configured with scientific software for cryoEM & other techniques; user-friendly Open OnDemand interface; seamless Slurm job submission.

  • Capsules isolate the software runtime environment, encapsulating executables, libraries, and version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. Learn more.

  • The Project MAC display system, circa 1965. Read more about the history of molecular graphics software and UCSF Chimera in our SBGrid Tale featuring Bob Langridge and Tom Ferrin.

  • Train the Trainer Workshops: continuing education for structural biology mentors on cryoEM data processing workflows; resources PIs can take back to the laboratory. Funded by NIH R25 GM151273.

  • Personal Installation Manager: a structural biology app store; users install preferred applications/ versions on laptops or personal workstations, with graphical or CLI interfaces for Mac or Linux. More details.

SBGrid Consortium homepage

Recent Software Updates

Software updates
Jul 29 | unicycler

Unicycler is an assembly pipeline for bacterial genomes. >>

Jul 28 | Boltz-1

an open-source model which predicts the 3D structure of proteins, rna, dna and small molecules; it handles modified residues, covalent liga… >>

Jul 23 | Volume_Seg_Tool

a tool that utilizes deep learning to perform volumetric electron microscopy image segmentations, both semantic and instance segmentation. >>

Jul 23 | cryoDRGN-AI

a neural network-based algorithm for ab initio heterogeneous cryo-EM reconstruction. >>

Jul 23 | autoPROC

a tool that combines third-party processing programs with new tools for automated data processing of single-sweep, multi-sweep and multi-cr… >>

Jul 23 | BUSTER

a software system containing crystallographic structure refinement using Bayesian statistical methods (BUSTER), ligand fitting (rhofit) and… >>

Jul 23 | rs-station_abismal

is f scaling and merging for large diffraction datasets using stochastic variational inference and deep learning. >>

Jul 18 | UGENE

a free open-source bioinformatics software for macOS, and Linux. >>

Jul 18 | RDKit

a collection of cheminformatics and machine-learning software written in C++ and Python. >>

Jul 17 | DenoisET

an implementation of the Noise2Noise algorithm specifically designed for cryoET data denoising. >>

Thanks to the National Science Foundation

With partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis; the NSF Research Coordination Network MCB #0639193, and NSF EAGER #1448069. Please cite SBGrid's eLife paper and follow our publication guidelines.

Latest news

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Read our June newsletter

Latest upgrades from SBGrid, including latest software updates, new members and special events. Published montly by SBGrid.

SBGrid Webinar Series

Join us for our Software Webinar Series - Tuesdays at 12pm ET - to hear from software developers about what's new in structural biology. Community members connect via Zoom. Subscribe …

SBGrid/Harvard Shield

Capsules Technology

We have recently published a manuscript describing our Capsules technology used to deploy SBGrid and BioGrids software collections. Read more in Acta Cryst Section D, special 75th ICUR anniversary issue, …

Connecting SBGrid with Instruct-ERIC

SBGrid is pleased to announce that it has established a partnership with Instruct-ERIC, based in Oxford, UK. Instruct-ERIC is a pan-European distributed research infrastructure with a hub in Oxford, UK …

The Final Phase

The Final Phase

For a person intent on tiny forms, George Phillips's career has been closely tied to big initiatives that have added new categories of structures to the Protein Data Bank. He …

Member publications

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