Supported Applications

RFdiffusion

Description

an open source method for structure generation, with or without conditional information (a motif, target etc). It can perform a whole range of protein design challenges.
Installation
Use the following command to install this title with the CLI client: $ sbgrid-cli install rfdiffusion Available operating systems: Linux 64
Primary Citation*

J. L. Watson, D. Juergens, N. R. Bennett, B. L. Trippe, J. Yim, H. E. Eisenach, W. Ahern, A. J. Borst, R. J. Ragotte, L. F. Milles, B. I. M. Wicky, N. Hanikel, S. J. Pellock, A. Courbet, W. Sheffler, J. Wang, P. Venkatesh, Sappington I, S. V. Torres, A. Lauko, D. Bortoli V, E. Mathieu, S. Ovchinnikov, R. Barzilay, T. S. Jaakkola, F. DiMaio, M. Baek, and D. Baker. 2023. De novo design of protein structure and function with RFdiffusion. Nature.
- *Full citation information available through

Keywords

Machine Learning, Protein-Protein Interaction Prediction, Protein Structure Analysis
Default Versions

Linux 64: 1.1.0 (9.1 GB)
Developers

David Baker, Joe Watson, Brian Trippe