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119 Member Publications for January 2019

Preface.
1. Methods Enzymol - published January 30, 2019
2. Bailey S
Preparation and electroporation of Cas12a/Cpf1-guide RNA complexes for introducing large gene deletions in mouse embryonic stem cells.
1. Methods Enzymol - published January 30, 2019
2. Kissling L, Monfort A, Swarts DC, Wutz A, Jinek M
Reconstitution of CRISPR adaptation in vitro and its detection by PCR.
1. Methods Enzymol - published January 30, 2019
2. Fagerlund RD, Ferguson TJ, Maxwell HWR, Opel-Reading HK, Krause KL, Fineran PC
Opening up about Tissue Transglutaminase: When Conformation Matters More than Enzymatic Activity.
1. Med One - published January 22, 2019
2. Katt WP, Antonyak MA, Cerione RA
Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates.
1. F1000Res - published January 17, 2019
2. Chao LH, Avruch J
Structure and belonging: Pathways to success for underrepresented minority and women PhD students in STEM fields.
1. PLoS One - published January 10, 2019
2. Fisher AJ, Mendoza-Denton R, Patt C, Young I, Eppig A, Garrell RL, Rees DC, Nelson TW, Richards MA
Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.
1. J Am Chem Soc - published January 9, 2019
2. Roushar FJ, Gruenhagen TC, Penn WD, Li B, Meiler J, Jastrzebska B, Schlebach JP
A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus.
1. Cell Host Microbe - published January 9, 2019
2. Uchil PD, Pi R, Haugh KA, Ladinsky MS, Ventura JD, Barrett BS, Santiago ML, Bjorkman PJ, Kassiotis G, Sewald X, Mothes W
In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex.
1. PLoS One - published January 9, 2019
2. Kumar A, Plückthun A
Modeling the complete chemokine-receptor interaction.
1. Methods Cell Biol - published January 9, 2019
2. Wedemeyer MJ, Mueller BK, Bender BJ, Meiler J, Volkman BF
In Vivo Expression of Mutant Calpains in the Eye Using Lentivirus.
1. Methods Mol Biol - published January 9, 2019
2. Wert KJ, Mahajan VB
Archiving of Integrative Structural Models.
1. Adv Exp Med Biol - published January 9, 2019
2. Berman HM, Trewhella J, Vallat B, Westbrook JD
HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design.
1. Cell Host Microbe - published January 9, 2019
2. Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, Shields JL, Lavine CL, Ghantous F, Rist M, Bayne MG, Neubauer GH, McMahan K, Peng H, Chéneau C, Jones JJ, Zeng J, Ochsenbauer C, Nkolola JP, Stephenson KE, Chen B, Gnanakaran S, Bonsignori M, Williams LD, Haynes BF, Doria-Rose N, Mascola JR, Montefiori DC, Barouch DH, Korber B
Protein Data Bank: the single global archive for 3D macromolecular structure data.
1. Nucleic Acids Res - published January 8, 2019
2. wwPDB consortium
Structural Analysis of the Active Site and DNA Binding of Human Cytidine Deaminase APOBEC3B.
1. J Chem Theory Comput - published January 8, 2019
2. Hou S, Silvas TV, Leidner F, Nalivaika EA, Matsuo H, Kurt Yilmaz N, Schiffer CA
The elemental mechanism of transcriptional pausing.
1. Elife - published January 8, 2019
2. Saba J, Chua XY, Mishanina TV, Nayak D, Windgassen TA, Mooney RA, Landick R
Mechanistic Insights into Microsecond Time-Scale Motion of Solid Proteins Using Complementary 15N and 1H Relaxation Dispersion Techniques.
1. J Am Chem Soc - published January 8, 2019
2. Rovó P, Smith CA, Gauto D, de Groot BL, Schanda P, Linser R
Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions.
1. Nat Commun - published January 8, 2019
2. Carravilla P, Chojnacki J, Rujas E, Insausti S, Largo E, Waithe D, Apellaniz B, Sicard T, Julien JP, Eggeling C, Nieva JL
A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System.
1. Mol Cell - published January 8, 2019
2. Wright AV, Wang JY, Burstein D, Harrington LB, Paez-Espino D, Kyrpides NC, Iavarone AT, Banfield JF, Doudna JA
Isotopic Labeling of Eukaryotic Membrane Proteins for NMR Studies of Interactions and Dynamics.
1. Methods Enzymol - published January 7, 2019
2. Dikiy I, Clark LD, Gardner KH, Rosenbaum DM
Combining NMR Spectroscopy and Molecular Dynamic Simulations to Solve and Analyze the Structure of Protein-RNA Complexes.
1. Methods Enzymol - published January 7, 2019
2. Campagne S, Krepl M, Sponer J, Allain FH
Nonuniform Sampling for NMR Spectroscopy.
1. Methods Enzymol - published January 7, 2019
2. Robson S, Arthanari H, Hyberts SG, Wagner G
TRAPPing a Rab GTPase by the Tail.
1. Dev Cell - published January 7, 2019
2. Duan J, Lambright DG
Recombinant Expression, Purification, and Assembly of p62 Filaments.
1. Methods Mol Biol - published January 6, 2019
2. Tarafder AK, Guesdon A, Kuhm T, Sachse C
In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells.
1. Bio Protoc - published January 5, 2019
2. Savić N, Ringnalda FC, Berk C, Bargsten K, Hall J, Jinek M, Schwank G
Detection of D-glutamate production from the dual Function enzyme, 4-amino-4-deoxychorismate Lyase/D-amino Acid Transaminase, in Mycobacterium smegmatis.
1. Bio Protoc - published January 5, 2019
2. Opel-Reading HK, Mortuza R, Krause KL
In vitro reconstitution of Wnt acylation reveals structural determinants of substrate recognition by the acyltransferase human Porcupine.
1. J Biol Chem - published January 4, 2019
2. Lee CJ, Rana MS, Bae C, Li Y, Banerjee A
Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis.
1. Chem Rev - published January 4, 2019
2. Marinko JT, Huang H, Penn WD, Capra JA, Schlebach JP, Sanders CR
Viral Delivery Systems for CRISPR.
1. Viruses - published January 4, 2019
2. Xu CL, Ruan MZC, Mahajan VB, Tsang SH
Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
1. Autophagy - published January 4, 2019
2. Lee EF, Smith NA, Soares da Costa TP, Meftahi N, Yao S, Harris TJ, Tran S, Pettikiriarachchi A, Perugini MA, Keizer DW, Evangelista M, Smith BJ, Fairlie WD
A Nucleosome Bridging Mechanism for Activation of a Maintenance DNA Methyltransferase.
1. Mol Cell - published January 3, 2019
2. Stoddard CI, Feng S, Campbell MG, Liu W, Wang H, Zhong X, Bernatavichute Y, Cheng Y, Jacobsen SE, Narlikar GJ
Deprescribing benzodiazepine receptor agonists taken for insomnia: a review and key messages from practice guidelines.
1. Pol Arch Intern Med - published January 3, 2019
2. Lee JY, Farrell B, Holbrook AM
Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists.
1. Nat Commun - published January 3, 2019
2. Schöppe J, Ehrenmann J, Klenk C, Rucktooa P, Schütz M, Doré AS, Plückthun A
Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
1. Nat Commun - published January 3, 2019
2. Lai YT, Wang T, O'Dell S, Louder MK, Schön A, Cheung CSF, Chuang GY, Druz A, Lin B, McKee K, Peng D, Yang Y, Zhang B, Herschhorn A, Sodroski J, Bailer RT, Doria-Rose NA, Mascola JR, Langley DR, Kwong PD
Probing the Dynamics and Structural Topology of the Reconstituted Human KCNQ1 Voltage Sensor Domain (Q1-VSD) in Lipid Bilayers Using Electron Paramagnetic Resonance Spectroscopy.
1. Biochemistry - published January 3, 2019
2. Dixit G, Sahu ID, Reynolds WD, Wadsworth TM, Harding BD, Jaycox CK, Dabney-Smith C, Sanders CR, Lorigan GA
A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
1. J Am Chem Soc - published January 3, 2019
2. Kreitler DF, Yao Z, Steinkruger JD, Mortenson DE, Huang L, Mittal R, Travis BR, Forest KT, Gellman SH
Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II.
1. Molecules - published January 3, 2019
2. Miller MS, Maheshwari S, Shi W, Gao Y, Chu N, Soares AS, Cole PA, Amzel LM, Fuchs MR, Jakoncic J, Gabelli SB
Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.
1. Nat Commun - published January 3, 2019
2. Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N
Conformational Dynamics in the Core of Human Y145Stop Prion Protein Amyloid Probed by Relaxation Dispersion NMR.
1. Chemphyschem - published January 2, 2019
2. Shannon MD, Theint T, Mukhopadhyay D, Surewicz K, Surewicz WK, Marion D, Schanda P, Jaroniec CP
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling.
1. Structure - published January 2, 2019
2. Bonomi M, Hanot S, Greenberg CH, Sali A, Nilges M, Vendruscolo M, Pellarin R
HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
1. Nucleic Acids Res - published January 2, 2019
2. Pabis M, Popowicz GM, Stehle R, Fernández-Ramos D, Asami S, Warner L, García-Mauriño SM, Schlundt A, Martínez-Chantar ML, Díaz-Moreno I, Sattler M
Microsecond Protein Dynamics from Combined Bloch-McConnell and Near-Rotary-Resonance R1p Relaxation-Dispersion MAS NMR.
1. Chemphyschem - published January 2, 2019
2. Marion D, Gauto DF, Ayala I, Giandoreggio-Barranco K, Schanda P
Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
1. Nucleic Acids Res - published January 2, 2019
2. Kroupova A, Ivascu A, Reimão-Pinto MM, Ameres SL, Jinek M
Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.
1. Structure - published January 2, 2019
2. Chuang GY, Zhou J, Acharya P, Rawi R, Shen CH, Sheng Z, Zhang B, Zhou T, Bailer RT, Dandey VP, Doria-Rose NA, Louder MK, McKee K, Mascola JR, Shapiro L, Kwong PD
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.
1. J Clin Invest - published January 2, 2019
2. Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC
Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design.
1. J Med Chem - published January 2, 2019
2. Maddirala AR, Klein R, Pinkner JS, Kalas V, Hultgren SJ, Janetka JW
Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology.
1. J Med Chem - published January 2, 2019
2. Damalanka VC, Han Z, Karmakar P, O'Donoghue AJ, La Greca F, Kim T, Pant SM, Helander J, Klefström J, Craik CS, Janetka JW
NMR resonance assignments and secondary structure of a mutant form of the human KCNE1 channel accessory protein that exhibits KCNE3-like function.
1. Biomol NMR Assign - published January 2, 2019
2. Law CL, Sanders CR
Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
1. Proc Natl Acad Sci U S A - published January 2, 2019
2. Braffman NR, Piscotta FJ, Hauver J, Campbell EA, Link AJ, Darst SA
Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations.
1. Cell - published January 2, 2019
2. Wingler LM, Elgeti M, Hilger D, Latorraca NR, Lerch MT, Staus DP, Dror RO, Kobilka BK, Hubbell WL, Lefkowitz RJ
Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.
1. Cell - published January 2, 2019
2. Wingler LM, McMahon C, Staus DP, Lefkowitz RJ, Kruse AC
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.
1. Cell - published January 2, 2019
2. Krishna Kumar K, Shalev-Benami M, Robertson MJ, Hu H, Banister SD, Hollingsworth SA, Latorraca NR, Kato HE, Hilger D, Maeda S, Weis WI, Farrens DL, Dror RO, Malhotra SV, Kobilka BK, Skiniotis G
Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
1. Proc Natl Acad Sci U S A - published January 2, 2019
2. Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE Jr, Rossmann MG
Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses.
1. Proc Natl Acad Sci U S A - published January 2, 2019
2. Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE Jr, Meiler J
Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
1. ACS Chem Biol - published January 2, 2019
2. Feliciano PR, Drennan CL, Nonato MC
VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site.
1. Invest Ophthalmol Vis Sci - published January 2, 2019
2. Tang PH, Velez G, Tsang SH, Bassuk AG, Mahajan VB
Reconstituting the reticular ER network - mechanistic implications and open questions.
1. J Cell Sci - published January 2, 2019
2. Wang N, Rapoport TA
Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer.
1. Sci Signal - published January 2, 2019
2. Schwill M, Tamaskovic R, Gajadhar AS, Kast F, White FM, Plückthun A
Non-acylated Wnts Can Promote Signaling.
1. Cell Rep - published January 2, 2019
2. Speer KF, Sommer A, Tajer B, Mullins MC, Klein PS, Lemmon MA
Engineering of CRISPR-Cas12b for human genome editing.
1. Nat Commun - published January 2, 2019
2. Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F
Crystallographic Snapshots of the Zika Virus NS3 Helicase Help Visualize the Reactant Water Replenishment.
1. ACS Infect Dis - published January 2, 2019
2. Fang J, Jing X, Lu G, Xu Y, Gong P
An improved yeast surface display platform for the screening of nanobody immune libraries.
1. Sci Rep - published January 2, 2019
2. Uchański T, Zögg T, Yin J, Yuan D, Wohlkönig A, Fischer B, Rosenbaum DM, Kobilka BK, Pardon E, Steyaert J
Structural insights into the activation of metabotropic glutamate receptors.
1. Nature - published January 2, 2019
2. Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK
FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics.
1. Elife - published January 2, 2019
2. Nune M, Morgan MT, Connell Z, McCullough L, Jbara M, Sun H, Brik A, Formosa T, Wolberger C
The structure of the nucleoprotein of Influenza D shows that all Orthomyxoviridae nucleoproteins have a similar NPCORE, with or without a NPTAIL for nuclear transport.
1. Sci Rep - published January 2, 2019
2. Donchet A, Oliva J, Labaronne A, Tengo L, Miloudi M, C A Gerard F, Mas C, Schoehn G, W H Ruigrok R, Ducatez M, Crépin T
Extent and Origins of Functional Diversity in a Subfamily of Glycoside Hydrolases.
1. J Mol Biol - published January 2, 2019
2. Glasgow EM, Vander Meulen KA, Takasuka TE, Bianchetti CM, Bergeman LF, Deutsch S, Fox BG
Molecular basis of synaptic specificity by immunoglobulin superfamily receptors in Drosophila.
1. Elife - published January 2, 2019
2. Cheng S, Ashley J, Kurleto JD, Lobb-Rabe M, Park YJ, Carrillo RA, Özkan E
FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles.
1. Elife - published January 2, 2019
2. Azubel M, Carter SD, Weiszmann J, Zhang J, Jensen GJ, Li Y, Kornberg RD
Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10.
1. J Steroid Biochem Mol Biol - published January 2, 2019
2. Dimeloe S, Rice LV, Chen H, Cheadle C, Raynes J, Pfeffer P, Lavender P, Richards DF, Nyon MP, McDonnell JM, Kemper C, Gooptu B, Hawrylowicz CM
Structure-Based Vaccine Antigen Design.
1. Annu Rev Med - published January 2, 2019
2. Graham BS, Gilman MSA, McLellan JS
FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein.
1. Nat Microbiol - published January 2, 2019
2. Taguchi A, Welsh MA, Marmont LS, Lee W, Sjodt M, Kruse AC, Kahne D, Bernhardt TG, Walker S
Charge Transport Communication through DNA by Protein Fe-S Clusters: How Far Is Not Too Far?
1. ACS Cent Sci - published January 2, 2019
2. Syed A, Tainer JA
Minimal nanodisc without exogenous lipids for stabilizing membrane proteins in detergent-free buffer.
1. Biochim Biophys Acta Biomembr - published January 2, 2019
2. Salvador D, Glavier M, Schoehn G, Phan G, Taveau JC, Decossas M, Lecomte S, Mongrand S, Garnier C, Broutin I, Daury L, Lambert O
Structural characterization of the O-GlcNAc cycling enzymes: insights into substrate recognition and catalytic mechanisms.
1. Curr Opin Struct Biol - published January 2, 2019
2. Joiner CM, Li H, Jiang J, Walker S
Polymer conjugation of proteins as a synthetic post-translational modification to impact their stability and activity.
1. Polym Chem - published January 2, 2019
2. Wright TA, Page RC, Konkolewicz D
Crystal Structure of PigA: A Prolyl Thioester-Oxidizing Enzyme in Prodigiosin Biosynthesis.
1. Chembiochem - published January 1, 2019
2. Lee CC, Ko TP, Chen CT, Chan YT, Lo SY, Chang JY, Chen YW, Chung TF, Hsieh HJ, Hsiao CD, Wang AH
Protein-ligand pose and affinity prediction: Lessons from D3R Grand Challenge 3.
1. J Comput Aided Mol Des - published January 1, 2019
2. Koukos PI, Xue LC, Bonvin AMJJ
Diacylglycerol kinases: Relationship to other lipid kinases.
1. Adv Biol Regul - published January 1, 2019
2. Ma Q, Gabelli SB, Raben DM
Addressing the diagnostic gaps in pyruvate kinase deficiency: Consensus recommendations on the diagnosis of pyruvate kinase deficiency.
1. Am J Hematol - published January 1, 2019
2. Bianchi P, Fermo E, Glader B, Kanno H, Agarwal A, Barcellini W, Eber S, Hoyer JD, Kuter DJ, Maia TM, Mañu-Pereira MDM, Kalfa TA, Pissard S, Segovia JC, van Beers E, Gallagher PG, Rees DC, van Wijk R, with the endorsement of EuroBloodNet, the European Reference Network in Rare Hematological Diseases.
Aerobic Enzymes and Their Radical SAM Enzyme Counterparts in Tetrapyrrole Pathways.
1. Biochemistry - published January 1, 2019
2. Li B, Bridwell-Rabb J
Foot-and-Mouth Disease Virus Leader Protease Cleaves G3BP1 and G3BP2 and Inhibits Stress Granule Formation.
1. J Virol - published January 1, 2019
2. Visser LJ, Medina GN, Rabouw HH, de Groot RJ, Langereis MA, de Los Santos T, van Kuppeveld FJM
A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions.
1. Nat Microbiol - published January 1, 2019
2. Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE Jr, Pierson TC
Correcting errors in the BRCA1 warning system.
1. DNA Repair (Amst) - published January 1, 2019
2. Liang Y, Dearnaley WJ, Alden NA, Solares MJ, Gilmore BL, Pridham KJ, Varano AC, Sheng Z, Alli E, Kelly DF
Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
1. Mol Cell - published January 1, 2019
2. Jia N, Mo CY, Wang C, Eng ET, Marraffini LA, Patel DJ
Nucleosome structure and dynamics are coming of age.
1. Nat Struct Mol Biol - published January 1, 2019
2. Zhou K, Gaullier G, Luger K
Does stromal interaction molecule-1 have five senses?
1. Cell Calcium - published January 1, 2019
2. Stathopulos PB, Ikura M
Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors.
1. Eur J Med Chem - published January 1, 2019
2. Wu B, Jayakar SS, Zhou X, Titterton K, Chiara DC, Szabo AL, Savechenkov PY, Kent DE, Cohen JB, Forman SA, Miller KW, Bruzik KS
Structural basis of coreceptor recognition by HIV-1 envelope spike.
1. Nature - published January 1, 2019
2. Shaik MM, Peng H, Lu J, Rits-Volloch S, Xu C, Liao M, Chen B
High-grade Endometrial Carcinomas: Morphologic and Immunohistochemical Features, Diagnostic Challenges and Recommendations.
1. Int J Gynecol Pathol - published January 1, 2019
2. Murali R, Davidson B, Fadare O, Carlson JA, Crum CP, Gilks CB, Irving JA, Malpica A, Matias-Guiu X, McCluggage WG, Mittal K, Oliva E, Parkash V, Rutgers JKL, Staats PN, Stewart CJR, Tornos C, Soslow RA
Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
1. Nat Med - published January 1, 2019
2. Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA
CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions.
1. Nat Protoc - published January 1, 2019
2. Hultquist JF, Hiatt J, Schumann K, McGregor MJ, Roth TL, Haas P, Doudna JA, Marson A, Krogan NJ
DDX58 and Classic Singleton-Merten Syndrome.
1. J Clin Immunol - published January 1, 2019
2. Ferreira CR, Crow YJ, Gahl WA, Gardner PJ, Goldbach-Mansky R, Hur S, de Jesús AA, Nehrebecky M, Park JW, Briggs TA
Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification.
1. Proc Natl Acad Sci U S A - published January 1, 2019
2. Perry NA, Kaoud TS, Ortega OO, Kaya AI, Marcus DJ, Pleinis JM, Berndt S, Chen Q, Zhan X, Dalby KN, Lopez CF, Iverson TM, Gurevich VV
A Small Helical Bundle Prepares Primer Synthesis by Binding Two Nucleotides that Enhance Sequence-Specific Recognition of the DNA Template.
1. Cell - published January 1, 2019
2. Boudet J, Devillier JC, Wiegand T, Salmon L, Meier BH, Lipps G, Allain FH
Understanding molecular mechanisms in cell signaling through natural and artificial sequence variation.
1. Nat Struct Mol Biol - published January 1, 2019
2. Shah NH, Kuriyan J
Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides.
1. Proc Natl Acad Sci U S A - published January 1, 2019
2. Ripoll-Rozada J, Costa M, Manso JA, Maranha A, Miranda V, Sequeira A, Ventura MR, Macedo-Ribeiro S, Pereira PJB, Empadinhas N
Autonomously designed free-form 2D DNA origami.
1. Sci Adv - published January 1, 2019
2. Jun H, Zhang F, Shepherd T, Ratanalert S, Qi X, Yan H, Bathe M
Influenza Virus-Specific Human Antibody Repertoire Studies.
1. J Immunol - published January 1, 2019
2. Crowe JE Jr
Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding.
1. Nature - published January 1, 2019
2. Boyaci H, Chen J, Jansen R, Darst SA, Campbell EA
Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin.
1. Elife - published January 1, 2019
2. Miller AN, Vaisey G, Long SB
De novo design of potent and selective mimics of IL-2 and IL-15.
1. Nature - published January 1, 2019
2. Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labão-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, Pardo-Avila F, Castellanos J, Carter L, Stewart L, Riddell SR, Pepper M, Bernardes GJL, Dougan M, Garcia KC, Baker D
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification.
1. Cell - published January 1, 2019
2. Oakes BL, Fellmann C, Rishi H, Taylor KL, Ren SM, Nadler DC, Yokoo R, Arkin AP, Doudna JA, Savage DF
High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture.
1. Proc Natl Acad Sci U S A - published January 1, 2019
2. Marston DJ, Anderson KL, Swift MF, Rougie M, Page C, Hahn KM, Volkmann N, Hanein D
Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
1. Int J Mol Sci - published January 1, 2019
2. Barre A, Bourne Y, Van Damme EJM, Rougé P
High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
1. Elife - published January 1, 2019
2. Arragain B, Reguera J, Desfosses A, Gutsche I, Schoehn G, Malet H
Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation.
1. Nat Commun - published January 1, 2019
2. Kano Y, Gebregiworgis T, Marshall CB, Radulovich N, Poon BPK, St-Germain J, Cook JD, Valencia-Sama I, Grant BMM, Herrera SG, Miao J, Raught B, Irwin MS, Lee JE, Yeh JJ, Zhang ZY, Tsao MS, Ikura M, Ohh M
Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies.
1. Oncogenesis - published January 1, 2019
2. Chen J, Foroozesh M, Qin Z
Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network.
1. J Am Chem Soc - published January 1, 2019
2. Hu S, Offenbacher AR, Thompson EM, Gee CL, Wilcoxen J, Carr CAM, Prigozhin DM, Yang V, Alber T, Britt RD, Fraser JS, Klinman JP
The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
1. Blood - published January 1, 2019
2. Dong X, Leksa NC, Chhabra ES, Arndt JW, Lu Q, Knockenhauer KE, Peters RT, Springer TA
Utilizing guanine-coordinated Zn2+ ions to determine DNA crystal structures by single-wavelength anomalous diffraction.
1. Acta Crystallogr D Struct Biol - published January 1, 2019
2. Hou C, Tsodikov OV
Solving a specificity mystery.
1. Elife - published January 1, 2019
2. Zheng S, Kruse AC
Structure and mechanism of the ESCRT pathway AAA+ ATPase Vps4.
1. Biochem Soc Trans - published January 1, 2019
2. Han H, Hill CP
Patient Characteristics and General Practitioners' Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries.
1. J Gen Intern Med - published January 1, 2019
2. van der Ploeg MA, Streit S, Achterberg WP, Beers E, Bohnen AM, Burman RA, Collins C, Franco FG, Gerasimovska-Kitanovska B, Gintere S, Gomez Bravo R, Hoffmann K, Iftode C, Peštić SK, Koskela TH, Kurpas D, Maisonneuve H, Mallen CD, Merlo C, Mueller Y, Muth C, Petrazzuoli F, Rodondi N, Rosemann T, Sattler M, Schermer T, Šter MP, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Tuz C, Vaes B, Viegas RPA, Vinker S, Wallis KA, Zeller A, Gussekloo J, Poortvliet RKE
Cellular and Structural Studies of Eukaryotic Cells by Cryo-Electron Tomography.
1. Cells - published January 1, 2019
2. Weber MS, Wojtynek M, Medalia O
The p12 subunit of human polymerase δ uses an atypical PIP-box for molecular recognition of proliferating cell nuclear antigen (PCNA).
1. J Biol Chem - published January 1, 2019
2. Gonzalez-Magaña A, Ibáñez de Opakua A, Romano-Moreno M, Murciano-Calles J, Merino N, Luque I, Rojas AL, Onesti S, Blanco FJ, De Biasio A
Structural basis for substrate binding and specificity of a sodium-alanine symporter AgcS.
1. Proc Natl Acad Sci U S A - published January 1, 2019
2. Ma J, Lei HT, Reyes FE, Sanchez-Martinez S, Sarhan MF, Hattne J, Gonen T
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
1. Structure - published January 1, 2019
2. Teyra J, Singer AU, Schmitges FW, Jaynes P, Kit Leng Lui S, Polyak MJ, Fodil N, Krieger JR, Tong J, Schwerdtfeger C, Brasher BB, Ceccarelli DFJ, Moffat J, Sicheri F, Moran MF, Gros P, Eichhorn PJA, Lenter M, Boehmelt G, Sidhu SS
Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1.
1. Oncotarget - published January 1, 2019
2. Ow TJ, Fulcher CD, Thomas C, Broin PÓ, López A, Reyna DE, Smith RV, Sarta C, Prystowsky MB, Schlecht NF, Schiff BA, Rosenblatt G, Belbin TJ, Harris TM, Childs GC, Kawachi N, Guha C, Gavathiotis E
Characterization of Miscanthus cell wall polymers.
1. Glob Change Biol Bioenergy - published January 1, 2019
2. Schäfer J, Sattler M, Iqbal Y, Lewandowski I, Bunzel M