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99 Member Publications for September 2018

Strategies to Trap Enzyme-Substrate Complexes that Mimic Michaelis Intermediates During E3-Mediated Ubiquitin-Like Protein Ligation.
1. Methods Mol Biol - published September 23, 2018
2. Streich FC Jr, Lima CD
Competition Assay for Measuring Deubiquitinating Enzyme Substrate Affinity.
1. Methods Mol Biol - published September 23, 2018
2. Morgan MT, Wolberger C
EFab domain substitution as a solution to the light-chain pairing problem of bispecific antibodies.
1. MAbs - published September 15, 2018
2. Cooke HA, Arndt J, Quan C, Shapiro RI, Wen D, Foley S, Vecchi MM, Preyer M
Rapid Selection of High-Affinity Antibody scFv Fragments Using Ribosome Display.
1. Methods Mol Biol - published September 10, 2018
2. Dreier B, Plückthun A
Ruxolitinib Therapy Followed by Reduced Intensity Conditioning for Hematopoietic Cell Transplantation for Myelofibrosis - Myeloproliferative Disorders Research Consortium 114 study.
1. Biol Blood Marrow Transplant - published September 8, 2018
2. Gupta V, Kosiorek HE, Mead A, Klisovic RB, Galvin JP, Berenzon D, Yacoub A, Viswabandya A, Mesa RA, Goldberg J, Price L, Salama ME, Weinberg RS, Rampal R, Farnoud N, Dueck AC, Mascarenhas JO, Hoffman R
Patching a leak in an R1 university gateway STEM course.
1. PLoS One - published September 7, 2018
2. Lee S, Crane BR, Ruttledge T, Guelce D, Yee EF, Lenetsky M, Caffrey M, Johnsen WA, Lin A, Lu S, Rodriguez MA, Wague A, Wu K
Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
1. Proc Natl Acad Sci U S A - published September 7, 2018
2. Nelson CA, Wilen CB, Dai YN, Orchard RC, Kim AS, Stegeman RA, Hsieh LL, Smith TJ, Virgin HW, Fremont DH
Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.
1. Sci Rep - published September 7, 2018
2. Lin EYS, Silvian LF, Marcotte DJ, Banos CC, Jow F, Chan TR, Arduini RM, Qian F, Baker DP, Bergeron C, Hession CA, Huganir RL, Borenstein CF, Enyedy I, Zou J, Rohde E, Wittmann M, Kumaravel G, Rhodes KJ, Scannevin RH, Dunah AW, Guckian KM
In Vivo Evidence for ATPase-Dependent DNA Translocation by the Bacillus subtilis SMC Condensin Complex.
1. Mol Cell - published September 6, 2018
2. Wang X, Hughes AC, Brandão HB, Walker B, Lierz C, Cochran JC, Oakley MG, Kruse AC, Rudner DZ
Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells.
1. Elife - published September 6, 2018
2. Sabbagh MF, Heng JS, Luo C, Castanon RG, Nery JR, Rattner A, Goff LA, Ecker JR, Nathans J
Protein-protein interactions in "cis-AT" polyketide synthases.
1. Nat Prod Rep - published September 6, 2018
2. Dodge GJ, Maloney FP, Smith JL
Structural basis for activation of voltage sensor domains in an ion channel TPC1.
1. Proc Natl Acad Sci U S A - published September 6, 2018
2. Kintzer AF, Green EM, Dominik PK, Bridges M, Armache JP, Deneka D, Kim SS, Hubbell W, Kossiakoff AA, Cheng Y, Stroud RM
Systematic discovery of natural CRISPR-Cas12a inhibitors.
1. Science - published September 6, 2018
2. Watters KE, Fellmann C, Bai HB, Ren SM, Doudna JA
Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.
1. Proc Natl Acad Sci U S A - published September 5, 2018
2. Fu Q, Shaik MM, Cai Y, Ghantous F, Piai A, Peng H, Rits-Volloch S, Liu Z, Harrison SC, Seaman MS, Chen B, Chou JJ
Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance.
1. Nat Rev Cancer - published September 5, 2018
2. Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S
A Novel MCL-1 Inhibitor Combined with Venetoclax Rescues Venetoclax Resistant Acute Myelogenous Leukemia.
1. Cancer Discov - published September 5, 2018
2. Ramsey HE, Fischer MA, Lee T, Gorska AE, Arrate MP, Fuller L, Boyd KL, Strickland SA, Sensintaffar J, Hogdal LJ, Ayers GD, Olejniczak ET, Fesik SW, Savona MR
In Crystallo Selection to Establish New RNA Crystal Contacts.
1. Structure - published September 4, 2018
2. Shoffner GM, Wang R, Podell E, Cech TR, Guo F
Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers.
1. Cell Metab - published September 4, 2018
2. Huang F, Ni M, Chalishazar MD, Huffman KE, Kim J, Cai L, Shi X, Cai F, Zacharias LG, Ireland AS, Li K, Gu W, Kaushik AK, Liu X, Gazdar AF, Oliver TG, Minna JD, Hu Z, DeBerardinis RJ
A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-β-lactamase SPS-1.
1. Biochemistry - published September 4, 2018
2. Cheng Z, VanPelt J, Bergstrom A, Bethel C, Katko A, Miller C, Mason K, Cumming E, Zhang H, Kimble RL, Fullington S, Bretz SL, Nix JC, Bonomo RA, Tierney DL, Page RC, Crowder MW
A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
1. Proc Natl Acad Sci U S A - published September 4, 2018
2. Sadler JBA, Wenzel DM, Williams LK, Guindo-Martínez M, Alam SL, Mercader JM, Torrents D, Ullman KS, Sundquist WI, Martin-Serrano J
Selecting New RNA Crystal Contacts.
1. Structure - published September 4, 2018
2. Gomez A, Toor N
Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens.
1. J Biol Chem - published September 4, 2018
2. Smith RP, Mohanty B, Mowlaboccus S, Paxman JJ, Williams ML, Headey SJ, Wang G, Subedi P, Doak BC, Kahler CM, Scanlon MJ, Heras B
Crystallographic evidence for unexpected selective tyrosine hydroxylations in an aerated achiral Ru-papain conjugate.
1. Metallomics - published September 3, 2018
2. Cherrier MV, Amara P, Talbi B, Salmain M, Fontecilla-Camps JC
Quantitative progression of retinitis pigmentosa by optical coherence tomography angiography.
1. Sci Rep - published September 3, 2018
2. Jauregui R, Park KS, Duong JK, Mahajan VB, Tsang SH
Visualization of HIV-1 RNA Transcription from Integrated HIV-1 DNA in Reactivated Latently Infected Cells.
1. Viruses - published September 3, 2018
2. Ukah OB, Puray-Chavez M, Tedbury PR, Herschhorn A, Sodroski JG, Sarafianos SG
The Scribble Cell Polarity Module in the Regulation of Cell Signaling in Tissue Development and Tumorigenesis.
1. J Mol Biol - published September 2, 2018
2. Stephens R, Lim K, Portela M, Kvansakul M, Humbert PO, Richardson HE
Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA.
1. Nucleic Acids Res - published September 2, 2018
2. Greenwood J, Patel H, Cech TR, Cooper JP
Cell Polarity Regulation-From Atomic to Macroscopic Scale.
1. J Mol Biol - published September 2, 2018
2. Kvansakul M, Humbert PO
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.
1. ACS Chem Biol - published September 2, 2018
2. Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, Becht K, Kim ND, McKeown MR, Roberts JM, Zhang J, Sim T, Alessi DR, Bradner JE, Lizcano JM, Blacklow SC, Qi J, Xu X, Gray NS
A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors.
1. Mol Ther Methods Clin Dev - published September 2, 2018
2. Hartmann J, Münch RC, Freiling RT, Schneider IC, Dreier B, Samukange W, Koch J, Seeger MA, Plückthun A, Buchholz CJ
Building and Breaking Bonds via a Compact S-Propargyl-Cysteine to Chemically Control Enzymes and Modify Proteins.
1. Angew Chem Int Ed Engl - published September 2, 2018
2. Liu J, Cheng R, Wu H, Li S, Wang PG, DeGrado WF, Rozovsky S, Wang L
An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture.
1. ACS Synth Biol - published September 2, 2018
2. ElGamacy M, Coles M, Ernst P, Zhu H, Hartmann MD, Plückthun A, Lupas AN
Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor.
1. Mol Cell - published September 2, 2018
2. Doxtader KA, Wang P, Scarborough AM, Seo D, Conrad NK, Nam Y
Methylation of Structured RNA by the m⁶A Writer METTL16 Is Essential for Mouse Embryonic Development.
1. Mol Cell - published September 2, 2018
2. Mendel M, Chen KM, Homolka D, Gos P, Pandey RR, McCarthy AA, Pillai RS
Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.
1. J Med Chem - published September 2, 2018
2. Hodges TR, Abbott JR, Little AJ, Sarkar D, Salovich JM, Howes JE, Akan DT, Sai J, Arnold AL, Browning C, Burns MC, Sobolik T, Sun Q, Beesetty Y, Coker JA, Scharn D, Stadtmueller H, Rossanese OW, Phan J, Waterson AG, McConnell DB, Fesik SW
A Lifelong Passion for All Things Ribonucleic.
1. Cell - published September 2, 2018
2. Cech TR
A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase.
1. Nucleic Acids Res - published September 2, 2018
2. Liu W, Shi X, Gong P
A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
1. Cell Death Dis - published September 2, 2018
2. Suraweera CD, Caria S, Järvå M, Hinds MG, Kvansakul M
Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase.
1. Sci Rep - published September 2, 2018
2. Kreamer NNK, Chopra R, Caughlan RE, Fabbro D, Fang E, Gee P, Hunt I, Li M, Leon BC, Muller L, Vash B, Woods AL, Stams T, Dean CR, Uehara T
A partial reconstitution implicates DltD in catalyzing lipoteichoic acid D-alanylation.
1. J Biol Chem - published September 2, 2018
2. Wood BM, Santa-Maria JP Jr, Matano LM, Vickery CR, Walker S
The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation.
1. Nat Commun - published September 2, 2018
2. Lee HS, Lin Z, Chae S, Yoo YS, Kim BG, Lee Y, Johnson JL, Kim YS, Cantley LC, Lee CW, Yu H, Cho H
On the damage done to the structure of the T. acidophilum proteasome by electron radiation.
1. Protein Sci - published September 2, 2018
2. Wang J, Liu Z, Crabtree RH, Frank J, Moore PB
A Platform To Enhance Quantitative Single Molecule Localization Microscopy.
1. J Am Chem Soc - published September 2, 2018
2. Golfetto O, Wakefield DL, Cacao EE, Avery KN, Kenyon V, Jorand R, Tobin SJ, Biswas S, Gutierrez J, Clinton R, Ma Y, Horne DA, Williams JC, Jovanović-Talisman T
Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells.
1. Cell Rep - published September 2, 2018
2. Shiota H, Barral S, Buchou T, Tan M, Couté Y, Charbonnier G, Reynoird N, Boussouar F, Gérard M, Zhu M, Bargier L, Puthier D, Chuffart F, Bourova-Flin E, Picaud S, Filippakopoulos P, Goudarzi A, Ibrahim Z, Panne D, Rousseaux S, Zhao Y, Khochbin S
Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.
1. Sci Signal - published September 2, 2018
2. Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, Shenoy SK, Laporte SA, Rockman HA, Lefkowitz RJ
Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer.
1. Cell Rep - published September 2, 2018
2. Guerra RM, Bird GH, Harvey EP, Dharia NV, Korshavn KJ, Prew MS, Stegmaier K, Walensky LD
Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1.
1. Sci Signal - published September 2, 2018
2. Jamieson SA, Ruan Z, Burgess AE, Curry JR, McMillan HD, Brewster JL, Dunbier AK, Axtman AD, Kannan N, Mace PD
A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.
1. Nat Commun - published September 2, 2018
2. Foglizzo M, Middleton AJ, Burgess AE, Crowther JM, Dobson RCJ, Murphy JM, Day CL, Mace PD
Visualization of Ca<sup>2+</sup> loss from rotavirus during cell entry.
1. J Virol - published September 2, 2018
2. Salgado EN, Garcia Rodriguez B, Narayanaswamy N, Krishnan Y, Harrison SC
Mapping the Contact Sites of the Escherichia coli Division-Initiating Proteins FtsZ and ZapA by BAMG Cross-Linking and Site-Directed Mutagenesis.
1. Int J Mol Sci - published September 2, 2018
2. Roseboom W, Nazir MG, Meiresonne NY, Mohammadi T, Verheul J, Buncherd H, Bonvin AMJJ, de Koning LJ, de Koster CG, de Jong L, den Blaauwen T
AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A.
1. Nat Commun - published September 2, 2018
2. Davies AK, Itzhak DN, Edgar JR, Archuleta TL, Hirst J, Jackson LP, Robinson MS, Borner GHH
Structural Biology of the HEAT-Like Repeat Family of DNA Glycosylases.
1. Bioessays - published September 2, 2018
2. Shi R, Shen XX, Rokas A, Eichman BF
A small molecule regulator of tissue transglutaminase conformation inhibits the malignant phenotype of cancer cells.
1. Oncotarget - published September 2, 2018
2. Katt WP, Blobel NJ, Komarova S, Antonyak MA, Nakano I, Cerione RA
Archaeal DNA on the histone merry-go-round.
1. FEBS J - published September 1, 2018
2. Bhattacharyya S, Mattiroli F, Luger K
Real-world clinical applicability of pathogenicity predictors assessed on SERPINA1 mutations in alpha-1-antitrypsin deficiency.
1. Hum Mutat - published September 1, 2018
2. Giacopuzzi E, Laffranchi M, Berardelli R, Ravasio V, Ferrarotti I, Gooptu B, Borsani G, Fra A
Loss of specificity variants of WzxC suggest that substrate recognition is coupled with transporter opening in MOP-family flippases.
1. Mol Microbiol - published September 1, 2018
2. Sham LT, Zheng S, Yakhnina AA, Kruse AC, Bernhardt TG
Posaconazole inhibits dengue virus replication by targeting oxysterol-binding protein.
1. Antiviral Res - published September 1, 2018
2. Meutiawati F, Bezemer B, Strating JRPM, Overheul GJ, Žusinaite E, van Kuppeveld FJM, van Cleef KWR, van Rij RP
Direct Detection of Membrane-Inserting Fragments Defines the Translocation Pores of a Family of Pathogenic Toxins.
1. J Mol Biol - published September 1, 2018
2. Orrell KE, Tellgren-Roth Å, Di Bernardo M, Zhang Z, Cuviello F, Lundqvist J, von Heijne G, Nilsson I, Melnyk RA
Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast.
1. Genetics - published September 1, 2018
2. Higgins DA, Young MKM, Tremaine M, Sardi M, Fletcher JM, Agnew M, Liu L, Dickinson Q, Peris D, Wrobel RL, Hittinger CT, Gasch AP, Singer SW, Simmons BA, Landick R, Thelen MP, Sato TK
Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-Target Anticancer Activities.
1. ChemMedChem - published September 1, 2018
2. Spiegelman NA, Price IR, Jing H, Wang M, Yang M, Cao J, Hong JY, Zhang X, Aramsangtienchai P, Sadhukhan S, Lin H
Designed peptides that assemble into cross-α amyloid-like structures.
1. Nat Chem Biol - published September 1, 2018
2. Zhang SQ, Huang H, Yang J, Kratochvil HT, Lolicato M, Liu Y, Shu X, Liu L, DeGrado WF
Author Correction: Structural basis for the regulation of inositol trisphosphate receptors by Ca²⁺ and IP₃.
1. Nat Struct Mol Biol - published September 1, 2018
2. Paknejad N, Hite RK
GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism.
1. Dev Cell - published September 1, 2018
2. Tanimura N, Liao R, Wilson GM, Dent MR, Cao M, Burstyn JN, Hematti P, Liu X, Zhang Y, Zheng Y, Keles S, Xu J, Coon JJ, Bresnick EH
Applications of Parametrized NMR Spin Systems of Small Molecules.
1. Anal Chem - published September 1, 2018
2. Dashti H, Wedell JR, Westler WM, Tonelli M, Aceti D, Amarasinghe GK, Markley JL, Eghbalnia HR
Differential Conformational Dynamics Encoded by the Linker between Quasi RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein H.
1. J Am Chem Soc - published September 1, 2018
2. Penumutchu SR, Chiu LY, Meagher JL, Hansen AL, Stuckey JA, Tolbert BS
Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract.
1. J Am Soc Nephrol - published September 1, 2018
2. van der Ven AT, Connaughton DM, Ityel H, Mann N, Nakayama M, Chen J, Vivante A, Hwang DY, Schulz J, Braun DA, Schmidt JM, Schapiro D, Schneider R, Warejko JK, Daga A, Majmundar AJ, Tan W, Jobst-Schwan T, Hermle T, Widmeier E, Ashraf S, Amar A, Hoogstraaten CA, Hugo H, Kitzler TM, Kause F, Kolvenbach CM, Dai R, Spaneas L, Amann K, Stein DR, Baum MA, Somers MJG, Rodig NM, Ferguson MA, Traum AZ, Daouk GH, Bogdanović R, Stajić N, Soliman NA, Kari JA, El Desoky S, Fathy HM, Milosevic D, Al-Saffar M, Awad HS, Eid LA, Selvin A, Senguttuvan P, Sanna-Cherchi S, Rehm HL, MacArthur DG, Lek M, Laricchia KM, Wilson MW, Mane SM, Lifton RP, Lee RS, Bauer SB, Lu W, Reutter HM, Tasic V, Shril S, Hildebrandt F
MicroED structure of the NaK ion channel reveals a Na⁺ partition process into the selectivity filter.
1. Commun Biol - published September 1, 2018
2. Liu S, Gonen T
Reply to 'Concerns with yeast mitochondrial ADP/ATP carrier's integrity in DPC' and 'Dynamics and interactions of AAC3 in DPC are not functionally relevant'.
1. Nat Struct Mol Biol - published September 1, 2018
2. Yang Q, Brüschweiler S, Zhao L, Chou JJ
Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase.
1. ACS Chem Biol - published September 1, 2018
2. Dodge GJ, Ronnow D, Taylor RE, Smith JL
Structural principles of SNARE complex recognition by the AAA+ protein NSF.
1. Elife - published September 1, 2018
2. White KI, Zhao M, Choi UB, Pfuetzner RA, Brunger AT
Improving signal strength in serial crystallography with DIALS geometry refinement.
1. Acta Crystallogr D Struct Biol - published September 1, 2018
2. Brewster AS, Waterman DG, Parkhurst JM, Gildea RJ, Young ID, O'Riordan LJ, Yano J, Winter G, Evans G, Sauter NK
Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
1. Nat Commun - published September 1, 2018
2. Schütz S, Michel E, Damberger FF, Oplová M, Peña C, Leitner A, Aebersold R, Allain FH, Panse VG
Author Correction: Amine hemilability enables boron to mechanistically resemble either hydride or proton.
1. Nat Chem - published September 1, 2018
2. Lee CF, Diaz DB, Holownia A, Kaldas SJ, Liew SK, Garrett GE, Dudding T, Yudin AK
Transcription factor CBF-1 is critical for circadian gene expression by modulating WHITE COLLAR complex recruitment to the frq locus.
1. PLoS Genet - published September 1, 2018
2. Cao X, Liu X, Li H, Fan Y, Duan J, Liu Y, He Q
Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival.
1. Sci Rep - published September 1, 2018
2. Varghese RT, Young S, Pham L, Liang Y, Pridham KJ, Guo S, Murphy S, Kelly DF, Sheng Z
Regional Differences in Airway Epithelial Cells Reveal Tradeoff between Defense against Oxidative Stress and Defense against Rhinovirus.
1. Cell Rep - published September 1, 2018
2. Mihaylova VT, Kong Y, Fedorova O, Sharma L, Dela Cruz CS, Pyle AM, Iwasaki A, Foxman EF
Heterogeneous Catalytic Oxidation of Amides to Imides by Manganese Oxides.
1. Sci Rep - published September 1, 2018
2. Biswas S, Khanna HS, Nizami QA, Caldwell DR, Cavanaugh KT, Howell AR, Raman S, Suib SL, Nandi P
Influenza A Virus Infection Causes Chronic Lung Disease Linked to Sites of Active Viral RNA Remnants.
1. J Immunol - published September 1, 2018
2. Keeler SP, Agapov EV, Hinojosa ME, Letvin AN, Wu K, Holtzman MJ
Identification of Changing Ribosome Protein Compositions using Mass Spectrometry.
1. Proteomics - published September 1, 2018
2. Samir P, Brown CM, Rahul R, Sun M, Shen B, Li W, Frank J, Link AJ
Touch and tactile neuropathic pain sensitivity are set by corticospinal projections.
1. Nature - published September 1, 2018
2. Liu Y, Latremoliere A, Li X, Zhang Z, Chen M, Wang X, Fang C, Zhu J, Alexandre C, Gao Z, Chen B, Ding X, Zhou JY, Zhang Y, Chen C, Wang KH, Woolf CJ, He Z
Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis.
1. PLoS Negl Trop Dis - published September 1, 2018
2. Zarantonelli L, Suanes A, Meny P, Buroni F, Nieves C, Salaberry X, Briano C, Ashfield N, Da Silva Silveira C, Dutra F, Easton C, Fraga M, Giannitti F, Hamond C, Macías-Rioseco M, Menéndez C, Mortola A, Picardeau M, Quintero J, Ríos C, Rodríguez V, Romero A, Varela G, Rivero R, Schelotto F, Riet-Correa F, Buschiazzo A, Grupo de Trabajo Interinstitucional de Leptospirosis Consortium.
X-ray structure of full-length human RuvB-Like 2 - mechanistic insights into coupling between ATP binding and mechanical action.
1. Sci Rep - published September 1, 2018
2. Silva STN, Brito JA, Arranz R, Sorzano CÓS, Ebel C, Doutch J, Tully MD, Carazo JM, Carrascosa JL, Matias PM, Bandeiras TM
Phase Seperation.
1. J Mol Biol - published September 1, 2018
2. Forman-Kay JD, Kriwacki RW, Seydoux G
Development of an antibody fragment that stabilizes GPCR/G-protein complexes.
1. Nat Commun - published September 1, 2018
2. Maeda S, Koehl A, Matile H, Hu H, Hilger D, Schertler GFX, Manglik A, Skiniotis G, Dawson RJP, Kobilka BK
Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase.
1. J Biol Chem - published September 1, 2018
2. Grell TAJ, Kincannon WM, Bruender NA, Blaesi EJ, Krebs C, Bandarian V, Drennan CL
Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16.
1. PLoS Genet - published September 1, 2018
2. Shi CH, Rubel C, Soss SE, Sanchez-Hodge R, Zhang S, Madrigal SC, Ravi S, McDonough H, Page RC, Chazin WJ, Patterson C, Mao CY, Willis MS, Luo HY, Li YS, Stevens DA, Tang MB, Du P, Wang YH, Hu ZW, Xu YM, Schisler JC
Author Correction: Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression.
1. Nat Commun - published September 1, 2018
2. Zhang L, Zhou H, Li X, Vartuli RL, Rowse M, Xing Y, Rudra P, Ghosh D, Zhao R, Ford HL
Snapshots of a modified nucleotide moving through the confines of a DNA polymerase.
1. Proc Natl Acad Sci U S A - published September 1, 2018
2. Kropp HM, Dürr SL, Peter C, Diederichs K, Marx A
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.
1. Nat Commun - published September 1, 2018
2. Zhang T, Wei G, Millard CJ, Fischer R, Konietzny R, Kessler BM, Schwabe JWR, Brockdorff N
Publisher Correction: Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.
1. Nat Commun - published September 1, 2018
2. Partin AC, Ngo TD, Herrell E, Jeong BC, Hon G, Nam Y
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis.
1. Nature - published September 1, 2018
2. Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramirez-Moya J, Du P, Kim W, Tang S, Sliz P, Santisteban P, George RE, Richards WG, Wong KK, Locker N, Slack FJ, Gregory RI
Manganese acquisition is essential for virulence of Enterococcus faecalis.
1. PLoS Pathog - published September 1, 2018
2. Colomer-Winter C, Flores-Mireles AL, Baker SP, Frank KL, Lynch AJL, Hultgren SJ, Kitten T, Lemos JA
Structural investigation of a chaperonin in action reveals how nucleotide binding regulates the functional cycle.
1. Sci Adv - published September 1, 2018
2. Mas G, Guan JY, Crublet E, Debled EC, Moriscot C, Gans P, Schoehn G, Macek P, Schanda P, Boisbouvier J
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS.
1. ACS Med Chem Lett - published September 1, 2018
2. Abbott JR, Patel PA, Howes JE, Akan DT, Kennedy JP, Burns MC, Browning CF, Sun Q, Rossanese OW, Phan J, Waterson AG, Fesik SW
Combination therapy with anti-HIV-1 antibodies maintains viral suppression.
1. Nature - published September 1, 2018
2. Mendoza P, Gruell H, Nogueira L, Pai JA, Butler AL, Millard K, Lehmann C, Suárez I, Oliveira TY, Lorenzi JCC, Cohen YZ, Wyen C, Kümmerle T, Karagounis T, Lu CL, Handl L, Unson-O'Brien C, Patel R, Ruping C, Schlotz M, Witmer-Pack M, Shimeliovich I, Kremer G, Thomas E, Seaton KE, Horowitz J, West AP Jr, Bjorkman PJ, Tomaras GD, Gulick RM, Pfeifer N, Fätkenheuer G, Seaman MS, Klein F, Caskey M, Nussenzweig MC
Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
1. ACS Med Chem Lett - published September 1, 2018
2. Zhu J, Dong J, Batiste L, Unzue A, Dolbois A, Pascanu V, Śledź P, Nevado C, Caflisch A
Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation.
1. Structure - published September 1, 2018
2. Haddad JF, Yang Y, Takahashi YH, Joshi M, Chaudhary N, Woodfin A, Benyoucef A, Yeung S, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF
Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease.
1. Transl Vis Sci Technol - published September 1, 2018
2. Velez G, Tang PH, Cabral T, Cho GY, Machlab DA, Tsang SH, Bassuk AG, Mahajan VB
Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale.
1. Biophys J - published September 1, 2018
2. Kumar A, Anderson KL, Swift MF, Hanein D, Volkmann N, Schwartz MA