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126 Member Publications for August 2017

Retinal and choroidal angiogenesis: a review of new targets.
1. Int J Retina Vitreous - published August 25, 2017
2. Cabral T, Mello LGM, Lima LH, Polido J, Regatieri CV, Belfort R Jr, Mahajan VB
Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin.
1. Theranostics - published August 22, 2017
2. Kramer L, Renko M, Završnik J, Turk D, Seeger MA, Vasiljeva O, Grütter MG, Turk V, Turk B
Deletion of Cytoplasmic Double-Stranded RNA Sensors Does Not Uncover Viral Small Interfering RNA Production in Human Cells.
1. mSphere - published August 18, 2017
2. Schuster S, Tholen LE, Overheul GJ, van Kuppeveld FJM, van Rij RP
Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice.
1. PLoS One - published August 17, 2017
2. Chiuppesi F, Wussow F, Scharf L, Contreras H, Gao H, Meng Z, Nguyen J, Barry PA, Bjorkman PJ, Diamond DJ
Preparation of Disease-Related Protein Assemblies for Single Particle Electron Microscopy.
1. Methods Mol Biol - published August 16, 2017
2. Cameron Varano A, Harafuji N, Dearnaley W, Guay-Woodford L, Kelly DF
Unfolding of core nucleosomes by PARP-1 revealed by spFRET microscopy.
1. AIMS Genet - published August 15, 2017
2. Sultanov DC, Gerasimova NS, Kudryashova KS, Maluchenko NV, Kotova EY, Langelier MF, Pascal JM, Kirpichnikov MP, Feofanov AV, Studitsky VM
Reducing the Flexibility of Type II Dehydroquinase Enzyme for Inhibition - A Fragment-Based Approach and Molecular Dynamics Simulation Study.
1. ChemMedChem - published August 9, 2017
2. Peón A, Robles A, Blanco B, Convertino M, Thompson P, Hawkins AR, Caflisch A, Gonzalez-Bello C
Solid-state NMR H-N-(C)-H and H-N-C-C 3D/4D correlation experiments for resonance assignment of large proteins.
1. Chemphyschem - published August 9, 2017
2. Fraga H, Arnaud CA, Gauto DF, Audin MJC, Kurauskas V, Macek P, Krichel C, Guan JY, Boisbouvier J, Sprangers R, Breyton C, Schanda P
Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design.
1. Cell Host Microbe - published August 9, 2017
2. Crowe JE Jr
Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers.
1. Elife - published August 8, 2017
2. Raj GV, Sareddy GR, Ma S, Lee TK, Viswanadhapalli S, Li R, Liu X, Murakami S, Chen CC, Lee WR, Mann M, Krishnan SR, Manandhar B, Gonugunta VK, Strand D, Tekmal RR, Ahn JM, Vadlamudi RK
Editorial overview: Chemical genetics and epigenetics.
1. Curr Opin Chem Biol - published August 8, 2017
2. Gavathiotis E, Zhou MM
Dynamic Change of Transcription Pausing through Modulating NELF Protein Stability Regulates Granulocytic Differentiation.
1. Blood Adv - published August 8, 2017
2. Liu X, Gogate AA, Tastemel M, Malladi VS, Yao H, Nguyen K, Huang LJ, Bai X
Adsorption-Coupled Diffusion of Gold Nanoclusters within a Large-Pore Protein Crystal Scaffold.
1. J Phys Chem B - published August 7, 2017
2. Hartje LF, Munsky B, Ni TW, Ackerson CJ, Snow CD
Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9.
1. J Am Chem Soc - published August 7, 2017
2. Palermo G, Ricci CG, Fernando A, Basak R, Jinek M, Rivalta I, Batista VS, McCammon JA
Katanin spiral and ring structures shed light on power stroke for microtubule severing.
1. Nat Struct Mol Biol - published August 7, 2017
2. Zehr E, Szyk A, Piszczek G, Szczesna E, Zuo X, Roll-Mecak A
Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression.
1. Proc Natl Acad Sci U S A - published August 7, 2017
2. Krapivinsky G, Krapivinsky L, Renthal NE, Santa-Cruz A, Manasian Y, Clapham DE
3.3 Å structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport.
1. Proc Natl Acad Sci U S A - published August 7, 2017
2. Li X, Lu F, Trinh MN, Schmiege P, Seemann J, Wang J, Blobel G
Optical determination of the electronic coupling and intercalation geometry of thiazole orange homodimer in DNA.
1. J Chem Phys - published August 7, 2017
2. Cunningham PD, Bricker WP, Díaz SA, Medintz IL, Bathe M, Melinger JS
Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport.
1. Philos Trans R Soc Lond B Biol Sci - published August 5, 2017
2. Joh NH, Grigoryan G, Wu Y, DeGrado WF
Liposome Disruption Assay to Examine Lytic Properties of Biomolecules.
1. Bio Protoc - published August 5, 2017
2. Jimah JR, Schlesinger PH, Tolia NH
Membrane Lipid Screen to Identify Molecular Targets of Biomolecules.
1. Bio Protoc - published August 5, 2017
2. Jimah JR, Schlesinger PH, Tolia NH
The microbial metabolite desaminotyrosine protects from influenza through type I interferon.
1. Science - published August 4, 2017
2. Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS
A Prodomain Fragment from the Proteolytic Activation of Growth Differentiation Factor 11 Remains Associated with the Mature Growth Factor and Keeps It Soluble.
1. Biochemistry - published August 3, 2017
2. Pepinsky B, Gong BJ, Gao Y, Lehmann A, Ferrant J, Amatucci J, Sun Y, Bush M, Walz T, Pederson N, Cameron T, Wen D
Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.
1. J Neurosci - published August 3, 2017
2. Clements R, Turk R, Campbell KP, Wright KM
Cyclols Revisited: Facile Synthesis of Medium-Sized Cyclic Peptides.
1. Chemistry - published August 3, 2017
2. Mendoza-Sanchez R, Corless VB, Nguyen QNN, Bergeron-Brlek M, Frost J, Adachi S, Tantillo DJ, Yudin AK
Identification of essential genes for cancer immunotherapy.
1. Nature - published August 3, 2017
2. Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, Eil R, Sukumar M, Guijarro EP, Day CP, Robbins P, Feldman S, Merlino G, Zhang F, Restifo NP
Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation.
1. Neuron - published August 3, 2017
2. Cho C, Smallwood PM, Nathans J
The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.
1. Biochemistry - published August 3, 2017
2. Mathews II, Allison K, Robbins T, Lyubimov AY, Uervirojnangkoorn M, Brunger AT, Khosla C, DeMirci H, McPhillips SE, Hollenbeck M, Soltis M, Cohen AE
Tylophorine Analogs Allosterically Regulates Heat Shock Cognate Protein 70 And Inhibits Hepatitis C Virus Replication.
1. Sci Rep - published August 3, 2017
2. Wang Y, Lee S, Ha Y, Lam W, Chen SR, Dutschman GE, Gullen EA, Grill SP, Cheng Y, Fürstner A, Francis S, Baker DC, Yang X, Lee KH, Cheng YC
Pea PSII-LHCII supercomplexes form pairs by making connections across the stromal gap.
1. Sci Rep - published August 3, 2017
2. Albanese P, Melero R, Engel BD, Grinzato A, Berto P, Manfredi M, Chiodoni A, Vargas J, Sorzano CÓS, Marengo E, Saracco G, Zanotti G, Carazo JM, Pagliano C
GUIDES: sgRNA design for loss-of-function screens.
1. Nat Methods - published August 3, 2017
2. Meier JA, Zhang F, Sanjana NE
Analysis of DNA binding by human factor xeroderma pigmentosum complementation group A (XPA) provides insight into its interactions with nucleotide excision repair substrates.
1. J Biol Chem - published August 3, 2017
2. Sugitani N, Voehler MW, Roh MS, Topolska-Woś AM, Chazin WJ
A ligand divided: antagonist, agonist and analog control.
1. Biochem J - published August 3, 2017
2. Klein DE
CFTR structure.
1. J Cyst Fibros - published August 3, 2017
2. Callebaut I, Chong PA, Forman-Kay JD
Membrane transporter research in times of countless structures.
1. Biochim Biophys Acta - published August 3, 2017
2. Seeger MA
A Secondary Structural Element in a Wide Range of Fucosylated Glycoepitopes.
1. Chemistry - published August 2, 2017
2. Aeschbacher T, Zierke M, Smieško M, Collot M, Mallet JM, Ernst B, Allain FH, Schubert M
Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.
1. J Biol Chem - published August 2, 2017
2. Vernon RM, Chong PA, Lin H, Yang Z, Zhou Q, Aleksandrov AA, Dawson JE, Riordan JR, Brouillette CG, Thibodeau PH, Forman-Kay JD
Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.
1. Neuron - published August 2, 2017
2. Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT
Crystal structure of the N-terminal half of the traffic controller UL37 from Herpes Simplex virus Type 1.
1. J Virol - published August 2, 2017
2. Koenigsberg AL, Heldwein EE
Synthesis and self-assembly of cellulose microfibrils from reconstituted cellulose synthase.
1. Plant Physiol - published August 2, 2017
2. Cho SH, Purushotham P, Fang C, Maranas C, Díaz-Moreno SM, Bulone V, Zimmer J, Kumar M, Nixon BT
Functional and structural characterization of synthetic cardosin B-derived rennet.
1. Appl Microbiol Biotechnol - published August 2, 2017
2. Almeida CM, Manso JA, Figueiredo AC, Antunes L, Cruz R, Manadas B, Bur D, Pereira PJB, Faro C, Simões I
Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects.
1. Cell Mol Life Sci - published August 2, 2017
2. Baxter AA, Lay FT, Poon IKH, Kvansakul M, Hulett MD
Monovalent Cation Activation of the Radical SAM Enzyme Pyruvate Formate-Lyase Activating Enzyme.
1. J Am Chem Soc - published August 2, 2017
2. Shisler KA, Hutcheson RU, Horitani M, Duschene KS, Crain AV, Byer AS, Shepard EM, Rasmussen A, Yang J, Broderick WE, Vey JL, Drennan CL, Hoffman BM, Broderick JB
Sulfur as an Acceptor to Bromine in Biomolecular Halogen Bonds.
1. J Phys Chem Lett - published August 2, 2017
2. Ford MC, Saxton M, Ho PS
Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator.
1. J Med Chem - published August 2, 2017
2. Schubert M, Stichel J, Du Y, Tough IR, Sliwoski G, Meiler J, Cox HM, Weaver CD, Beck-Sickinger AG
Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
1. Nat Chem Biol - published August 2, 2017
2. Pancera M, Lai YT, Bylund T, Druz A, Narpala S, O'Dell S, Schön A, Bailer RT, Chuang GY, Geng H, Louder MK, Rawi R, Soumana DI, Finzi A, Herschhorn A, Madani N, Sodroski J, Freire E, Langley DR, Mascola JR, McDermott AB, Kwong PD
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
1. Proc Natl Acad Sci U S A - published August 2, 2017
2. Chan AH, Lee WG, Spasov KA, Cisneros JA, Kudalkar SN, Petrova ZO, Buckingham AB, Anderson KS, Jorgensen WL
How can the structure of germinal-center kinase-like kinase help us in drug discovery?
1. Future Med Chem - published August 2, 2017
2. Silvian L
Performance of HADDOCK and a simple contact-based protein-ligand binding affinity predictor in the D3R Grand Challenge 2.
1. J Comput Aided Mol Des - published August 2, 2017
2. Kurkcuoglu Z, Koukos PI, Citro N, Trellet ME, Rodrigues JPGLM, Moreira IS, Roel-Touris J, Melquiond ASJ, Geng C, Schaarschmidt J, Xue LC, Vangone A, Bonvin AMJJ
Flow-induced elongation of von Willebrand factor precedes tension-dependent activation.
1. Nat Commun - published August 2, 2017
2. Fu H, Jiang Y, Yang D, Scheiflinger F, Wong WP, Springer TA
Crystal Structure of Leiomodin 2 in Complex with Actin: A Structural and Functional Reexamination.
1. Biophys J - published August 2, 2017
2. Boczkowska M, Yurtsever Z, Rebowski G, Eck MJ, Dominguez R
The uncoupling of protease trans-cleavage and helicase activities in the pestivirus NS3.
1. J Virol - published August 2, 2017
2. Zheng F, Lu G, Li L, Gong P, Pan Z
Attenuated human parainfluenza virus type 1 (HPIV1) expressing the respiratory syncytial virus (RSV) fusion F glycoprotein from an added gene: effects of pre-fusion stabilization and packaging of RSV F.
1. J Virol - published August 2, 2017
2. Liu X, Liang B, Ngwuta J, Liu X, Surman S, Lingemann M, Kwong PD, Graham BS, Collins PL, Munir S
In Situ Capture of Chromatin Interactions by Biotinylated dCas9.
1. Cell - published August 2, 2017
2. Liu X, Zhang Y, Chen Y, Li M, Zhou F, Li K, Cao H, Ni M, Liu Y, Gu Z, Dickerson KE, Xie S, Hon GC, Xuan Z, Zhang MQ, Shao Z, Xu J
Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum.
1. Sci Rep - published August 2, 2017
2. Verchère A, Ou WL, Ploier B, Morizumi T, Goren MA, Bütikofer P, Ernst OP, Khelashvili G, Menon AK
Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor binding determinants.
1. J Biol Chem - published August 2, 2017
2. Gupta P, Zhang Z, Sugiman-Marangos SN, Tam J, Raman S, Julien JP, Kroh HK, Lacy DB, Murgolo N, Bekkari K, Therien AG, Hernandez LD, Melnyk RA
Structure of the Holliday junction: applications beyond recombination.
1. Biochem Soc Trans - published August 2, 2017
2. Ho PS
A Broad-Spectrum Inhibitor of CRISPR-Cas9.
1. Cell - published August 2, 2017
2. Harrington LB, Doxzen KW, Ma E, Liu JJ, Knott GJ, Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, Sontheimer EJ, Davidson AR, Maxwell KL, Doudna JA
Reversible protein aggregation is a protective mechanism to ensure cell cycle restart after stress.
1. Nat Cell Biol - published August 2, 2017
2. Saad S, Cereghetti G, Feng Y, Picotti P, Peter M, Dechant R
Beyond Cell-Cell Adhesion: Sensational Cadherins for Hearing and Balance.
1. Cold Spring Harb Perspect Biol - published August 2, 2017
2. Jaiganesh A, Narui Y, Araya-Secchi R, Sotomayor M
Glucosylsphingosine promotes α-synuclein pathology in mutant GBA-associated Parkinson's disease.
1. J Neurosci - published August 2, 2017
2. Taguchi YV, Liu J, Ruan J, Pacheco J, Zhang X, Abbasi J, Keutzer J, Mistry PK, Chandra SS
A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.
1. J Biol Chem - published August 2, 2017
2. Stiegler SC, Rübbelke M, Korotkov VS, Weiwad M, John C, Fischer G, Sieber SA, Sattler M, Buchner J
Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.
1. Sci Rep - published August 2, 2017
2. Schulz EC, Seiler M, Zuliani C, Voigt F, Rybin V, Pogenberg V, Mücke N, Wilmanns M, Gibson TJ, Barabas O
Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy.
1. Anesthesiology - published August 2, 2017
2. Ma C, Pejo E, McGrath M, Jayakar SS, Zhou X, Miller KW, Cohen JB, Raines DE
Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.
1. Nucleic Acids Res - published August 2, 2017
2. Mutisya D, Hardcastle T, Cheruiyot SK, Pallan PS, Kennedy SD, Egli M, Kelley ML, Smith AVB, Rozners E
Genetic characterization of Guinea-Bissau using a 12 X-chromosomal STR system: Inferences from a multiethnic population.
1. Forensic Sci Int Genet - published August 2, 2017
2. Gomes I, Pereira PJP, Harms S, Oliveira AM, Schneider PM, Brehm A
Curvature of designed armadillo repeat proteins allows modular peptide binding.
1. J Struct Biol - published August 2, 2017
2. Hansen S, Ernst P, König SLB, Reichen C, Ewald C, Nettels D, Mittl PRE, Schuler B, Plückthun A
Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses.
1. Cell Host Microbe - published August 2, 2017
2. Lauber C, Seitz S, Mattei S, Suh A, Beck J, Herstein J, Börold J, Salzburger W, Kaderali L, Briggs JAG, Bartenschlager R
Snapshots of the Signaling Complex DesK:DesR in Different Functional States Using Rational Mutagenesis and X-ray Crystallography.
1. Bio Protoc - published August 2, 2017
2. Imelio JA, Larrieux N, Mechaly AE, Trajtenberg F, Buschiazzo A
Structure and elevator mechanism of the Na⁺-citrate transporter CitS.
1. Curr Opin Struct Biol - published August 1, 2017
2. Lolkema JS, Slotboom DJ
Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors.
1. J Neurochem - published August 1, 2017
2. Molgó J, Marchot P, Aráoz R, Benoit E, Iorga BI, Zakarian A, Taylor P, Bourne Y, Servent D
Global Protease Activity Profiling Provides Differential Diagnosis of Pancreatic Cysts.
1. Clin Cancer Res - published August 1, 2017
2. Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.
1. Arthritis Rheumatol - published August 1, 2017
2. Wilkinson DJ, Wang H, Habgood A, Lamb HK, Thompson P, Hawkins AR, Désilets A, Leduc R, Steinmetzer T, Hammami M, Lee MS, Craik CS, Watson S, Lin H, Milner JM, Rowan AD
Clostridium difficile toxins A and B: Receptors, pores, and translocation into cells.
1. Crit Rev Biochem Mol Biol - published August 1, 2017
2. Orrell KE, Zhang Z, Sugiman-Marangos SN, Melnyk RA
Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface.
1. Mol Pharmacol - published August 1, 2017
2. Hudson RP, Dawson JE, Chong PA, Yang Z, Millen L, Thomas PJ, Brouillette CG, Forman-Kay JD
Rapid convergence of optimal control in NMR using numerically-constructed toggling frames.
1. J Magn Reson - published August 1, 2017
2. Coote P, Anklin C, Massefski W, Wagner G, Arthanari H
Engineered Cpf1 variants with altered PAM specificities.
1. Nat Biotechnol - published August 1, 2017
2. Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F
Optimized fast mixing device for real-time NMR applications.
1. J Magn Reson - published August 1, 2017
2. Franco R, Favier A, Schanda P, Brutscher B
Conformational Control of UDP-Galactopyranose Mutase Inhibition.
1. Biochemistry - published August 1, 2017
2. Wangkanont K, Winton VJ, Forest KT, Kiessling LL
Polymorphic Nature of Human T-Cell Leukemia Virus Type 1 Particle Cores as Revealed through Characterization of a Chronically Infected Cell Line.
1. J Virol - published August 1, 2017
2. Meissner ME, Mendonça LM, Zhang W, Mansky LM
Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.
1. J Clin Invest - published August 1, 2017
2. Miles LA, Burga LN, Gardner EE, Bostina M, Poirier JT, Rudin CM
Mechanism of pathogen recognition by human dectin-2.
1. J Biol Chem - published August 1, 2017
2. Feinberg H, Jégouzo SAF, Rex MJ, Drickamer K, Weis WI, Taylor ME
Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition.
1. J Biol Chem - published August 1, 2017
2. Maheshwari S, Miller MS, O'Meally R, Cole RN, Amzel LM, Gabelli SB
Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury.
1. Proc Natl Acad Sci U S A - published August 1, 2017
2. Chou A, Krukowski K, Jopson T, Zhu PJ, Costa-Mattioli M, Walter P, Rosi S
Uncovering the secrets of protein interactions with the DNA enforcing genomic stability.
1. Prog Biophys Mol Biol - published August 1, 2017
2. Tainer JA
Sense and Simplicity in HADDOCK Scoring: Lessons from CASP-CAPRI (page 418).
1. Proteins - published August 1, 2017
2. Vangone A, Rodrigues JPGLM, Xue LC, van Zundert GCP, Geng C, Kurkcuoglu Z, Nellen M, Narasimhan S, Karaca E, van Dijk M, Melquiond ASJ, Visscher KM, Trellet M, Kastritis PL, Bonvin AMJJ
Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases.
1. J Am Chem Soc - published August 1, 2017
2. Acker TM, Gable JE, Bohn MF, Jaishankar P, Thompson MC, Fraser JS, Renslo AR, Craik CS
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.
1. Nat Commun - published August 1, 2017
2. Roymans D, Alnajjar SS, Battles MB, Sitthicharoenchai P, Furmanova-Hollenstein P, Rigaux P, Berg JVD, Kwanten L, Ginderen MV, Verheyen N, Vranckx L, Jaensch S, Arnoult E, Voorzaat R, Gallup JM, Larios-Mora A, Crabbe M, Huntjens D, Raboisson P, Langedijk JP, Ackermann MR, McLellan JS, Vendeville S, Koul A
Silencing repetitive DNA.
1. Elife - published August 1, 2017
2. Iglesias N, Moazed D
Backbone and side chain resonance assignments for a structured domain within Atg32.
1. Biomol NMR Assign - published August 1, 2017
2. Xia X, Pellegrini M, Ragusa MJ
High-resolution structure of a Kazal-type serine protease inhibitor from the dengue vector Aedes aegypti.
1. Acta Crystallogr F Struct Biol Commun - published August 1, 2017
2. Torquato RJS, Lu S, Martins NH, Tanaka AS, Pereira PJB
Protein-nucleic acids interactions: new ways of connecting structure, dynamics and function.
1. Biophys Rev - published August 1, 2017
2. Spies M, Smith BO
Structural and functional analyses of the spliceosome requires a multi-disciplinary approach.
1. Methods - published August 1, 2017
2. Ohi MD
Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
1. Mol Cell - published August 1, 2017
2. Yamano T, Zetsche B, Ishitani R, Zhang F, Nishimasu H, Nureki O
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.
1. Nature - published August 1, 2017
2. Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F
Filovirus Structural Biology: The Molecules in the Machine.
1. Curr Top Microbiol Immunol - published August 1, 2017
2. Kirchdoerfer RN, Wasserman H, Amarasinghe GK, Saphire EO
The ATAD2 Bromodomain Binds Different Acetylation Marks on the Histone H4 in Similar Fuzzy Complexes.
1. J Biol Chem - published August 1, 2017
2. Langini C, Caflisch A, Vitalis A
Structure of histone-based chromatin in Archaea.
1. Science - published August 1, 2017
2. Mattiroli F, Bhattacharyya S, Dyer PN, White AE, Sandman K, Burkhart BW, Byrne KR, Lee T, Ahn NG, Santangelo TJ, Reeve JN, Luger K
Effects of fluorophore attachment on protein conformation and dynamics studied by spFRET and NMR.
1. Chemistry - published August 1, 2017
2. Sanchez C, Voith-von-Voithenberg L, Warner L, Lamb DC, Sattler M
Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers.
1. Sci Rep - published August 1, 2017
2. Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM
TRF2 binds branched DNA to safeguard telomere integrity.
1. Nat Struct Mol Biol - published August 1, 2017
2. Schmutz I, Timashev L, Xie W, Patel DJ, de Lange T
M3: an integrative framework for structure determination of molecular machines.
1. Nat Methods - published August 1, 2017
2. Karaca E, Rodrigues JPGLM, Graziadei A, Bonvin AMJJ, Carlomagno T
Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation.
1. Proc Natl Acad Sci U S A - published August 1, 2017
2. Gu S, Sachleben JR, Boughter CT, Nawrocka WI, Borowska MT, Tarrasch JT, Skiniotis G, Roux B, Adams EJ
SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots.
1. Sci Rep - published August 1, 2017
2. Moreira IS, Koukos PI, Melo R, Almeida JG, Preto AJ, Schaarschmidt J, Trellet M, Gümüş ZH, Costa J, Bonvin AMJJ
Structural analyses of the bacterial primosomal protein DnaB reveal that it is a tetramer and forms a complex with a primosomal re-initiation protein.
1. J Biol Chem - published August 1, 2017
2. Li YC, Naveen V, Lin MG, Hsiao CD
Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activation.
1. J Biol Chem - published August 1, 2017
2. Yao XQ, Cato MC, Labudde E, Beyett TS, Tesmer JJG, Grant BJ
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
1. Proc Natl Acad Sci U S A - published August 1, 2017
2. Pallesen J, Wang N, Corbett KS, Wrapp D, Kirchdoerfer RN, Turner HL, Cottrell CA, Becker MM, Wang L, Shi W, Kong WP, Andres EL, Kettenbach AN, Denison MR, Chappell JD, Graham BS, Ward AB, McLellan JS
Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure.
1. Nature - published August 1, 2017
2. Liu X, Ahn S, Kahsai AW, Meng KC, Latorraca NR, Pani B, Venkatakrishnan AJ, Masoudi A, Weis WI, Dror RO, Chen X, Lefkowitz RJ, Kobilka BK
The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.
1. Nature - published August 1, 2017
2. Zhou Q, Zhou P, Wang AL, Wu D, Zhao M, Südhof TC, Brunger AT
Pictures of the prologue to neurotransmitter release.
1. Proc Natl Acad Sci U S A - published August 1, 2017
2. Harrison SC
Expression and purification of a difficult sarcomeric protein: Telethonin.
1. Protein Expr Purif - published August 1, 2017
2. Tan H, Su W, Wang P, Zhang W, Sattler M, Zou P
The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling.
1. Mol Biol Cell - published August 1, 2017
2. Viswanath S, Bonomi M, Kim SJ, Klenchin VA, Taylor KC, Yabut KC, Umbreit NT, Van Epps HA, Meehl J, Jones MH, Russel D, Velazquez-Muriel JA, Winey M, Rayment I, Davis TN, Sali A, Muller EG
A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions.
1. Neuron - published August 1, 2017
2. Liu Y, Wang X, Li W, Zhang Q, Li Y, Zhang Z, Zhu J, Chen B, Williams PR, Zhang Y, Yu B, Gu X, He Z
Backbone and side-chain resonance assignments of (Ca2+)4-calmodulin bound to beta calcineurin A CaMBD peptide.
1. Biomol NMR Assign - published August 1, 2017
2. Fowler CA, Núñez Hernandez MF, O'Donnell SE, Yu L, Shea MA
Engineering defined membrane-embedded elements of AMPA receptor induces opposing gating modulation by CNIH3 and stargazin.
1. J Physiol - published August 1, 2017
2. Hawken N, Zaika E, Nakagawa T
Light Scattering By Optically-Trapped Vesicles Affords Unprecedented Temporal Resolution Of Lipid-Raft Dynamics.
1. Sci Rep - published August 1, 2017
2. Collard L, Perez-Guaita D, Faraj BHA, Wood BR, Wallis R, Andrew PW, Hudson AJ
Vinculin forms a directionally asymmetric catch bond with F-actin.
1. Science - published August 1, 2017
2. Huang DL, Bax NA, Buckley CD, Weis WI, Dunn AR
Carbon and amide detect backbone assignment methods of a novel repeat protein from the staphylocoagulase in S. aureus.
1. Biomol NMR Assign - published August 1, 2017
2. Voehler M, Ashoka MA, Meiler J, Bock PE
Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.
1. Cell Chem Biol - published August 1, 2017
2. Totzke J, Gurbani D, Raphemot R, Hughes PF, Bodoor K, Carlson DA, Loiselle DR, Bera AK, Eibschutz LS, Perkins MM, Eubanks AL, Campbell PL, Fox DA, Westover KD, Haystead TAJ, Derbyshire ER
Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography.
1. J Biomol Struct Dyn - published August 1, 2017
2. Peters JP, Kowal EA, Pallan PS, Egli M, Maher LJ 3rd
Chemical synthesis of guanosine diphosphate mannuronic acid (GDP-ManA) and its C-4-O-methyl and C-4-deoxy congeners.
1. Carbohydr Res - published August 1, 2017
2. Zhang Q, Howell PL, Overkleeft HS, Filippov DV, van der Marel GA, Codée JDC
Deconstruction of the Beaten Path-Sidestep interaction network provides insights into neuromuscular system development.
1. Elife - published August 1, 2017
2. Li H, Watson A, Olechwier A, Anaya M, Sorooshyari SK, Harnett DP, Lee HP, Vielmetter J, Fares MA, Garcia KC, Özkan E, Labrador JP, Zinn K
A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
1. Elife - published August 1, 2017
2. Sdano MA, Fulcher JM, Palani S, Chandrasekharan MB, Parnell TJ, Whitby FG, Formosa T, Hill CP
Analysis of IgG kinetic stability by differential scanning calorimetry, probe fluorescence and light scattering.
1. Protein Sci - published August 1, 2017
2. Nemergut M, Žoldák G, Schaefer JV, Kast F, Miškovský P, Plückthun A, Sedlák E
Discovery of BAZ2A bromodomain ligands.
1. Eur J Med Chem - published August 1, 2017
2. Spiliotopoulos D, Wamhoff EC, Lolli G, Rademacher C, Caflisch A
Complete Genome of Achalarus lyciades, The First Representative of the Eudaminae Subfamily of Skippers.
1. Curr Genomics - published August 1, 2017
2. Shen J, Cong Q, Borek D, Otwinowski Z, Grishin NV