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  • Description

    (Diffraction Integration for Advanced Light Sources) a software project for the analysis of crystallographic diffraction images for many new methods from shutterless, fine-sliced rotation scans to randomly-oriented snapshots of serial crystallography. It uses multiple CPU and GPU machines to increase speed and accuracy based on a comprehensive physical model.

  • Usage

    To list all executables provided by DIALS, run: $ sbgrid-list dials Copy to clipboard
  • Usage Notes

    Version control for DIALS is described on

  • Installation

    Use the following command to install this title with the CLI client: $ sbgrid-cli install dials Copy to clipboard Available operating systems: Linux 64, OS X INTEL
  • Primary Citation*

    G. Winter, J. Beilsten-Edmands, N. Devenish, M. Gerstel, R. J. Gildea, D. McDonagh, E. Pascal, D. G. Waterman, B. H. Williams, and G. Evans. 2022. DIALS as a toolkit. Protein science : a publication of the Protein Society. 31(1): 232-250.

    • *Full citation information available through

  • Citation Note

    A full list of citations can also be found on the DIALS website.

  • Tales

    Turning the DIALS

    Turning the DIALS

    Nicholas Sauter began working on DIALS (Diffraction Integration for Advanced Light Sources) in 2011 because he and his colleagues recognized that the experimental methods of X-ray crystallography were changing, and changing fast. To be usable, the software that automates crystallography experiments must be able to keep up.

    So he and his team at Lawrence Berkeley National Laboratory and collaborating teams at CCP4 and at the Diamond Light Source synchrotron in the United Kingdom developed a modular system that allows new algorithms to be dropped in as new experimental methods and technologies emerge. Examples include handling data from faster detectors, like the Pilatus, handling new technologies, such as the X-ray free electron laser (XFEL), and handling new types of experiments, such as putting multiple crystals in the beamline at …

    Read the full story here.
  • Webinars

    DIALS- what’s new - with a focus on treatment of multi-crystal data sets.

    SBGrid webinars are hosted with partial support from the NIH R25 Continuing Education for Structural Biology Mentors #GM151273, in collaboration with Co-PI Jamaine Davis of Meharry Medical College.

    Topic: DIALS - what’s new - with a focus on treatment of multi-crystal data sets.

    Presenter: Graeme Winter, Ph.D., Senior Software Scientist / Team Lead, Diamond Light Source

    Host: Pete Meyer
    Recorded on January 9, 2023

    For more information on DIALS:


    Topic: Processing serial crystallographic data using cctbx.xfel and DIALS
    Presenter: Aaron Brewster, Project Scientist, Lawrence Berkeley National Laboratory

    Host: Jason Key
    Recorded on January 10, 2016


    Topic: DIALS
    Presenter: Graeme Winter, Scientist, Diamond Light Source

    Host: Jason Key
    Recorded on November 17, 2015

    Lecture 14:  DIALS:  Advanced Data Reduction

    Topic: DIALS: Advanced Data Reduction
    Presenter: Nicholas Sauter, Lawrence Berkeley National Labs

    Presented as part of:
    SBGrid/NE-CAT 2014: Data Processing in Crystallography
    June 5-6, 2014

  • Keywords


  • Default Versions

    Linux 64:  3.19.0 (2.0 GB)
    OS X INTEL:  3.19.0 (2.1 GB)

  • Other Versions

      Linux 64:

      2.2.3 (1.5 GB) , 3.13.0 (2.0 GB) , 3.14.2 (3.9 GB) , 3.17.0 (2.0 GB) , 3.18.0 (2.0 GB)
    • OS X INTEL:

      2.2.3 (1.2 GB) , 3.13.0 (1.7 GB) , 3.14.2 (1.7 GB) , 3.17.0 (1.7 GB) , 3.18.0 (2.1 GB)
  • Developers

    Gwyndaf Evans, Nick Sauter