Supported Applications


  • Description

    (Diffraction Integration for Advanced Light Sources) a software project for the analysis of crystallographic diffraction images designed to cope with the ever increasing volumes and rates of data collection, and with the developments in experimental methodology, from shutterless, fine-sliced rotation scans through to the randomly-oriented snapshots of serial crystallography. This software utilizes techniques of parallel processing using multiple CPU and GPU machines, facilitating not just speed, but highly accurate analysis based on a comprehensive physical model.

  • Primary Citation*

    D. G. Waterman, G. Winter, J. M. Parkhurst, L. Fuentes-Montero, J. Hattne, A. Brewster, N. K. Sauter, and G. Evans. 2013. The DIALS framework for integration software. CCP4 Newsletter on Protein Crystallography. 49: 13-15.

    • *Full citation information available through

  • Categories


  • Default Versions

    Linux 64 1.4.5
    OS X INTEL 1.4.5

  • Other Available Versions

    Linux 64 1.4.1
    Linux 64 1.4.2
    Linux 64 1.4.3
    OS X INTEL 1.4.1
    OS X INTEL 1.4.2
    OS X INTEL 1.4.3

  • Developers

    Gwyndaf Evans, Nick Sauter, Graeme Winter.

  • Tales

    Turning the DIALS

    Turning the DIALS

    Nicholas Sauter began working on DIALS (Diffraction Integration for Advanced Light Sources) in 2011 because he and his colleagues recognized that the experimental methods of X-ray crystallography were changing, and changing fast. To be usable, the software that automates crystallography experiments must be able to keep up.

    So he and his team at Lawrence Berkeley National Laboratory and collaborating teams at CCP4 and at the Diamond Light Source synchrotron in the United Kingdom developed a modular system that allows new algorithms to be dropped in as new experimental methods and technologies emerge. Examples include handling data from faster detectors, like the Pilatus, handling new technologies, such as the X-ray free electron laser (XFEL), and handling new types of experiments, such as putting multiple crystals in the beamline at ...

    Read More.