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SBGridTV

Supported Applications

ACE2

  • Description

    a CTF Estimator. ACE2 is a completely rewritten version of ACE. ACE2 adds the additional feature of robust astigmatism estimation and CTF correction with astigmatism using either a mild Weiner filter (recommended) or phase-flipping. Since ACE2 is written in objective C, it no longer requires MATLAB to work.

  • Categories

    Electron Microscopy

  • Default Versions

    Linux 64 1.0
    OS X INTEL 1.0

  • Other Available Versions

    Linux 32 1.0

  • Developers

    Bridget Carragher, Clint Potter.

  • Tales

    Pipeline Dreams

    Pipeline Dreams

    A year ago, Bridget Carragher and Clint Potter’s group broke the so-called three-angstrom barrier for electron microscopy (EM). Prior to their work, so many structures had been solved using EM at 3.4 or 3.5-angstrom resolution that people had started to believe higher resolutions were out of reach with the technology.

    "Our group set out to show that EM could do better,” says Carragher, co-Director of the Simons Electron Microscopy Center (SEMC) at the New York Structural Biology Center (NYSBC). “We did things carefully and in a fully automated fashion and got to 2.8 angstroms. That was the first time anyone was able to see water molecules in an EM structure."


    Water molecules from an EM structure. Campbell MG, Veesler D, Cheng A, Potter CS ...

    Read More.