Rosetta

  • a software suite for predicting and designing protein structures, protein folding mechanisms, and protein-protein interactions. ROSETTA has been consistently successful in CASP and CAPRI competitions. Rosetta is also used for improving NMR and homology models before they are used in molecular replacement. Application developed and maintained by Baker Laboratory at the University of Washington.

Developers

Rosetta Licensing

Alan Yen

Rosetta Developer Team

Categories

Computational Chemistry

Versions

Citations

Fleishman et al. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science (New York, NY) (2011) vol. 332 (6031) pp. 816-21

Wang et al. Modeling disordered regions in proteins using rosetta. PloS one (2011) vol. 6 (7) pp. e22060

DiMaio et al. Refinement of protein structures into low-resolution density maps using rosetta. Journal of molecular biology (2009) vol. 392 (1) pp. 181-90

Ramelot et al. Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. Proteins (2009) vol. 75 (1) pp. 147-67

Rigden et al. Molecular replacement using ab initio polyalanine models generated with ROSETTA. Acta crystallographica Section D, Biological crystallography (2008) vol. 64 (Pt 12) pp. 1288-91

Technical Notes

Redistribution is permitted required that members are all academic labs.

License Type

This software is distributed under a Non-Profit license.

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